Morphofunctional Characteristics of the Umbilical Vessels from Newborns Delivered by Mothers Experiencing an Exacerbation of Chronic Cytomegalovirus Infection during Gestation

Michael T. Lucenko, PhD, ScD*, Irina A. Andrievskaya, PhD, ScD.

Far Eastern Scientific Center of Physiology and Pathology of Respiration, Siberian Branch of Russian Academy of Medical Sciences, Blagoveshchensk, Russian Federation

*Corresponding author: Prof. Michael T. Lucenko, PhD, ScD, Academician of RAMS, Head of Far Eastern Scientific Center of Physiology and Pathology of Respiration SB of RAMS, 95A, Gorky str., 675000, Blagoveshchensk, Russian Federation. Phone: 8 -416-2-52-2922 E-mail: Lucencomt@mail.ru

Published: June 25, 2013

Abstract: 

The characteristic features of the cord blood and endothelium of the umbilical vessels from newborns delivered by mothers experiencing an exacerbation of chronic cytomegalovirus (CMV) infection during gestation has been studied. Exacerbation of the chronic CMV infection was found to increase during pregnancy and sharply affect the function of gas transport in both the maternal and fetal blood. Lipid peroxidation in the maternal blood as well as in the fetal blood was seen to increase, which was reflected in the characteristic endothelial structure and enzymatic activity in the umbilical vessels of the newborns.

Keywords: 
umbilical cord; gas-transport function; lipid peroxidation.
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Int J Biomed. 2013; 3(2):112-114. © 2013 International Medical Research and Development Corporation. All rights reserved.