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A two-step screening protocol that combines clinical risk assessment with biomarker testing can more effectively identify which patients with Type 2 diabetes need medication to prevent heart failure, according to a study led by UT Southwestern Medical Center researchers.

Preeclampsia and other hypertensive disorders of pregnancy-;which are characterized by high blood pressure with or without organ dysfunction during the second half of pregnancy-;carry considerable short- and long-term risks for both the mother and child. Treatment options (other than expedited delivery) remain limited.

A new study from researchers at the University of Colorado Anschutz Medical Campus finds that older adult drivers who are recently diagnosed with migraines are three times as likely to experience a motor vehicle crash.

A type of immune cell can help predict which patients may benefit most from cancer immunotherapies, researchers from King's College London, Guy's and St Thomas' Hospital Trust, and the Francis Crick Institute have found.

Yale researchers have identified a drug target that may alleviate joint degeneration associated with osteoarthritis, a debilitating condition that afflicts as many as 30 million people in the United States alone, which they report on Jan. 3 in the journal Nature.

Researchers at the Del Monte Institute for Neuroscience at the University of Rochester find that microglia-;the brain's immune cells-;can trigger cognitive deficits after radiation exposure and may be a key target for preventing these symptoms.

Cleveland Clinic and the University of Western Ontario have been awarded a $4.9 million grant from Helmsley Charitable Trust to build a consortium to develop clinical trial outcome tools for patients with Crohn's disease and permanent ileostomy.