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Yale scientists identify drug target that may alleviate joint degeneration in osteoarthritis

Rss Feed - Wed, 01/03/2024 - 13:13
Yale researchers have identified a drug target that may alleviate joint degeneration associated with osteoarthritis, a debilitating condition that afflicts as many as 30 million people in the United States alone, which they report on Jan. 3 in the journal Nature.

Brain's immune cells may be a key target for preventing cognitive deficits after radiation exposure

Rss Feed - Wed, 01/03/2024 - 13:03
Researchers at the Del Monte Institute for Neuroscience at the University of Rochester find that microglia-;the brain's immune cells-;can trigger cognitive deficits after radiation exposure and may be a key target for preventing these symptoms.

$4.9 million grant awarded to build EndO-trial consortium for improving the lives of Crohn's patients

Rss Feed - Wed, 01/03/2024 - 12:33
Cleveland Clinic and the University of Western Ontario have been awarded a $4.9 million grant from Helmsley Charitable Trust to build a consortium to develop clinical trial outcome tools for patients with Crohn's disease and permanent ileostomy.

Existing beta blocker investigated as novel sickle cell therapy

Rss Feed - Wed, 01/03/2024 - 12:24
A beta blocker typically used to treat heart problems, hemangioma, migraines and anxiety could be a new therapeutic for patients with sickle cell disease. Researchers led by Ankit A. Desai, MD, associate professor of medicine at the Krannert Cardiovascular Research Center (KCVRC) at Indiana University School of Medicine, have been awarded a $3 million grant by the U.S. Department of Defense to evaluate the efficacy of this drug.

New research project seeks to find innovative treatment pathways for Type 2 diabetes and obesity

Rss Feed - Wed, 01/03/2024 - 12:15
A team of Virginia Tech researchers was awarded nearly $2 million from the National Institute of Diabetes and Digestive and Kidney Disease, part of the National Institutes of Health, to explore novel approaches for treating Type 2 diabetes and obesity.

Mapping tiny corneal nerves to untangle ocular mysteries

Rss Feed - Wed, 01/03/2024 - 12:06
Consider the cornea if you will – and most people won't unless they're having a problem. It is the transparent front surface of the eye which allows vision by focusing light as it enters.

New synthetic antibiotic found to be more effective than established drugs against 'superbugs'

Rss Feed - Wed, 01/03/2024 - 12:01
A new synthetic antibiotic developed by University of Liverpool researchers is shown to be more effective than established drugs against 'superbugs' such as MRSA, a new study shows.

"Genetic priority score" promises to revolutionize drug development

Rss Feed - Wed, 01/03/2024 - 11:48
Driven by the need for a better way to prioritize targets for drug development, the Icahn School of Medicine at Mount Sinai has led the development of a novel "genetic priority score" (GPS) that will integrate various types of human genetic data into a single easy-to-interpret score.

Researchers identify microbial enzyme responsible for making urine yellow

Rss Feed - Wed, 01/03/2024 - 09:50
Researchers at the University of Maryland and National Institutes of Health have identified the microbial enzyme responsible for giving urine its yellow hue, according to a new study published in the journal Nature Microbiology on January 3, 2024.

New standardized criteria for diagnosing brain tumors with amino acid PET

Rss Feed - Wed, 01/03/2024 - 08:46
Diffuse gliomas are malignant brain tumors that cannot be optimally examined by means of conventional MRI imaging. So-called amino acid PET scans are better able to image the activity and spread of gliomas.

Heart-healthy diet boosts patient satisfaction and safety before cardiac catheterization

Rss Feed - Wed, 01/03/2024 - 08:41
The days of prolonged fasting prior to cardiac catheterization may be numbered, as the body of evidence grows to allow patients to eat before the procedure.

Novel exercise approach offers significant benefits for children with cerebral palsy

Rss Feed - Wed, 01/03/2024 - 08:23
Children with cerebral palsy (CP) have reported significant gains in cardiovascular fitness and mobility after taking part in a landmark research project led by The University of Queensland.

Artificial intelligence is a promising tool to disseminate nutrition-related information, study finds

Rss Feed - Wed, 01/03/2024 - 06:19
The accuracy and reliability of nutrition information provided by two versions of ChatGPT.

EGCG effect: Study suggests green tea compound may ease inflammatory iron deficiency

Rss Feed - Wed, 01/03/2024 - 05:51
Whether a polyphenol found in green tea, reduces inflammation.

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