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Multiomic approach boosts disease prediction accuracy beyond traditional methods

Rss Feed - Tue, 03/26/2024 - 22:41
Study highlights the significant enhancement in predicting common diseases like heart disease, diabetes, Alzheimer's, and prostate cancer by integrating polygenic risk scores (PRSs) and gut microbiome scores with conventional risk factors, showcasing the potential of multiomic approaches in personalized medicine.

Hidden brain changes found to common in people with a range of heart conditions

Rss Feed - Tue, 03/26/2024 - 21:25
A new analysis involving over 13,000 people has found changes to blood vessels in the brain that can increase the risk of stroke and dementia are common in people with a range of heart conditions, regardless of whether they have experienced a stroke.

Antioxidant-rich diets linked to lower type 2 diabetes risk, supplements less effective

Rss Feed - Tue, 03/26/2024 - 19:51
Study systematically reviews the impact of dietary antioxidants, vitamins C, E, and beta-carotene, on reducing the risk of type 2 diabetes, suggesting an inverse association with the disease, though no protective effects from supplementation were observed.

ABT199/venetoclax synergism with thiotepa enhances cytotoxicity of chemo drugs in AML cells

Rss Feed - Tue, 03/26/2024 - 15:49
A new research paper was published in Oncotarget's Volume 15 on March 14, 2024, entitled, "ABT199/venetoclax synergism with thiotepa enhances the cytotoxicity of fludarabine, cladribine and busulfan in AML cells."

Study identifies key priorities for building mental health-friendly cities for young people

Rss Feed - Tue, 03/26/2024 - 15:11
As cities around the world continue to draw young people for work, education, and social opportunities, a new study identifies characteristics that would support young urban dwellers' mental health.

Study unveils link between oral bacteria and pancreatic cancer development in mice

Rss Feed - Tue, 03/26/2024 - 13:13
New study unveils a significant connection between oral bacteria and pancreatic cancer development in mice and sheds light on a previously recognized link between oral health and pancreatic cancer, one of the deadliest forms of cancer.

Study reveals genetic variant linked to increased risk of leukemia in Hispanic/Latino children

Rss Feed - Tue, 03/26/2024 - 13:02
Acute lymphoblastic leukemia (ALL), the most common childhood cancer, disproportionately affects children of Hispanic/Latino origin in the United States.

Sedentary time in childhood associated with premature vascular damage

Rss Feed - Tue, 03/26/2024 - 12:52
Increase in sedentary time from childhood is associated with worsening arterial stiffness, a surrogate for premature vascular damage, a new study shows.

Study reveals trigonelline as a therapeutic agent for mitochondrial dysfunction in aging

Rss Feed - Tue, 03/26/2024 - 10:34
Sarcopenia is the age-related decline in skeletal muscle due to the wasting of myofiber.

Vitamin D shows promise in targeting aging's biological mechanisms, study finds

Rss Feed - Tue, 03/26/2024 - 07:37
What is currently known about the potential effect of vitamin D (VitD) on modulating some hallmarks of aging.

Global fight against TB misses 2020 WHO milestones, despite progress in certain age groups

Rss Feed - Tue, 03/26/2024 - 07:11
The global, national, and regional burden and trends in tuberculosis.

Comprehensive study reveals global total fertility rate more than halved since 1950

Rss Feed - Tue, 03/26/2024 - 06:48
Comprehensive estimates of past and future trends in fertility across 204 nations and territories from 1950 to 2100.

Towards better diagnosis of neurodegenerative disorders: Skin biopsy for α-synuclein detection proves effective

Rss Feed - Tue, 03/26/2024 - 06:20
The positivity rate of cutaneous phosphorylated alpha-synuclein protein (P-SYN) deposition among individuals with dementia.

Emerging trends in wearable breath sensors aim at personalized healthcare solutions

Rss Feed - Tue, 03/26/2024 - 05:38
Using wearable breath sensors to monitor respiratory parameters such as temperature, airflow, and humidity, and to detect various respiratory biomarkers.

Study unveils protein signatures for early detection of endometrial cancer in cervico-vaginal fluid

Rss Feed - Tue, 03/26/2024 - 04:52
Proteomic signatures in blood plasma and cervicovaginal fluid for endometrial cancer detection.

Mediterranean diet linked to lower dementia risk, finds extensive review

Rss Feed - Tue, 03/26/2024 - 01:23
Meta-analysis reveals a positive link between adherence to the Mediterranean diet and a reduced risk of dementia, particularly Alzheimer's disease, among older adults, highlighting the diet's potential as a modifiable risk factor in dementia prevention strategies.

EAT-Lancet diet adherence shrinks waistlines but not weight over five years

Rss Feed - Mon, 03/25/2024 - 23:48
Study found no significant relationship between adherence to the EAT-Lancet diet and body weight changes after five years but identified a slight inverse association with waist circumference, indicating a potential benefit in reducing obesity risk and waist size in the long term.

Urgent care needed for stroke survivors facing long-term depression

Rss Feed - Mon, 03/25/2024 - 23:37
Researchers say more needs to be done for depressed stroke survivors as new findings show 60% of stroke survivors would experience depression within 18 years, a much higher estimation than previous studies.

Molnupiravir influences SARS-CoV-2 evolution in immunocompromised patients

Rss Feed - Mon, 03/25/2024 - 23:32
Study found that the antiviral molnupiravir affects the evolution of SARS-CoV-2 in immunocompromised patients, suggesting its use modifies viral mutation patterns and may impact viral evolution.

Feedback loop involving estrogen linked to women's higher propensity to nicotine addiction

Rss Feed - Mon, 03/25/2024 - 23:31
A newly discovered feedback loop involving estrogen may explain why women might become dependent on nicotine more quickly and with less nicotine exposure than men.

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