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Proteasomes: Expanding roles beyond cellular waste management
The typical job of the proteasome, the garbage disposal of the cell, is to grind down proteins into smaller bits and recycle some of those bits and parts.
NJHF awards $135K to Kessler Foundation scientists for pilot research projects
This year, New Jersey Health Foundation (NJHF) granted $135,000 in awards to three Kessler Foundation scientists to support pilot research projects that exhibit promising potential.
Understanding the role of genetic variants in male infertility
Approximately one in seven couples face difficulties conceiving a child naturally. Half of these cases are due to male infertility – either caused by the complete absence or low number of mature sperm.
Breakthrough study reveals melanoma's resistance tactics to targeted therapy
Melanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to alleviate the health burden of the disease. Important advances in recent years include doctors using genetic tests to look for specific mutations they can target for more personalised, effective treatment.
Study assesses how the Dobbs ruling changed permanent contraception procedures among young adults
The first study to evaluate the effect of the Dobbs v. Jackson Women's Health Organization ruling on permanent contraception procedures among young adults nationwide was published today in a JAMA Health Forum research letter.
Genetic predisposition for muscle strength linked to longer lifespan and lower disease risk
A study conducted at the Faculty of Sport and Health Sciences at the University of Jyväskylä, Finland, showed that a genetic predisposition for higher muscle strength predicts a longer lifespan and a lower risk for developing common diseases.
Study shows exercise can reverse age-related lipid accumulation
Scientists have discovered that a type of fat accumulates as tissue ages and that this accumulation can be reversed through exercise.
Seafood is a potentially underestimated source of PFAS exposure, study shows
A Dartmouth-led study suggests that people who frequently consume seafood may face an increased risk of exposure to PFAS, the family of ubiquitous and resilient human-made toxins known as "forever chemicals."
Normothermic regional perfusion could increase the number of patients receiving lung transplants
Re-perfusing the lungs of an organ donor after the heart has irreversibly stopped beating with a technique called normothermic regional perfusion (TA-NRP) could potentially increase the number of patients receiving lung transplants, according to researchers at the Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT) in Prague.
Soft tumor environments prime cancer cells for survival during metastasis
Researchers have discovered how the mechanical properties of tumors can prime cancer cells to better survive their spread to other organs.
Study finds dysfunction of key brain systems in people with psychosis
Inside the brains of people with psychosis, two key systems are malfunctioning: a "filter" that directs attention toward important external events and internal thoughts, and a "predictor" composed of pathways that anticipate rewards.
Addressing public health challenges through behavioral interventions
The concept of "One Health" – which emphasizes the relationship between human, animal, plant and environmental health – has been gaining ground in scientific discussions in recent years.
Childhood verbal abuse costs global society $300 billion annually, study finds
Childhood verbal abuse by adults costs society an estimated $300 billion (£239 billion) a year globally, show findings presented at the first international conference on childhood verbal abuse, hosted by UCL, Words Matter and the World Health Organization (WHO).
Neural circuitry in the spinal cord allows brain-independent motor learning
Aya Takeoka at the RIKEN Center for Brain Science (CBS) in Japan and colleagues have discovered the neural circuitry in the spinal cord that allows brain-independent motor learning.
Women predominantly treated for anxiety and depression at psychiatric outpatient clinics
More than 75% of the patients treated at the psychiatric outpatient clinic of Hospital de Base in São José do Rio Preto, São Paulo state (Brazil), are women with a mean age of 45 and suffering from sadness, anxiety and irritability, according to a study reported in the journal Frontiers in Psychiatry.
Study reveals metabolic markers linked to long COVID-19 severity
Long COVID-19, or post-acute sequelae of SARS-CoV-2 infection (PASC), is a global health phenomenon characterized by persistent symptoms following the acute phase of COVID-19.
Intraoperative anemia linked to higher female mortality after heart bypass surgery
Women are at higher risk of death when undergoing heart bypass surgery than men. Researchers at Weill Cornell Medicine have determined that this disparity is mediated, to a large extent, by intraoperative anemia-;the loss of red blood cells during surgery.
New murine model sheds light on anti-MDA5 antibody-positive dermatomyositis
Some diseases involve autoimmune reactions, when the body begins to attack its own cells and proteins.
Hypertensive disorders in pregnancy strongly associated with cardiovascular mortality after giving birth
Rutgers Health researchers have found that hypertensive disorders in pregnancy are strongly associated with fatal cardiovascular disease for up to a year after birth.
Research sheds light on post-sepsis immune suppression mechanism
Severe sepsis from bacterial or viral infections can be life-threatening and even people recovering from severe sepsis may experience long-lasting effects on the immune system, making them more susceptible to recurrent infections.