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Study shows SARS-CoV-2 uses a receptor to efficiently infect human cells

Rss Feed - Wed, 10/21/2020 - 10:23
To efficiently infect human cells, SARS-CoV-2, the virus that causes COVID-19, is able to use a receptor called Neuropilin-1, which is very abundant in many human tissues including the respiratory tract, blood vessels and neurons.

Researchers use supercomputers to simulate the inner working of Ebola virus

Rss Feed - Wed, 10/21/2020 - 10:16
As the world grapples with the coronavirus (COVID-19) pandemic, another virus has been raging again in the Democratic Republic of the Congo in recent months: Ebola.

Researchers quantify reduction in volume of cough cloud in the presence of face mask

Rss Feed - Wed, 10/21/2020 - 10:07
As the coronavirus has affected more than 30 million people globally, researchers have increasingly focused on the extent to which airborne respiratory droplets carrying the virus travel and contaminate the air after an infected person coughs.

Study uses computational fluid-particle dynamics to explore aerosol transport in classroom model

Rss Feed - Wed, 10/21/2020 - 10:01
As the COVID-19 virus continues to spread around the globe, studying aerosol and droplet transport within different environments can help establish effective, physics-informed measures for virus mitigation.

Researchers explore SARS-CoV-2 at single cell resolution in human airway epithelial cells

Rss Feed - Wed, 10/21/2020 - 09:45
The cellular tropism of the SARS-CoV-2 virus affects several aspects of infection, such as the spread of the virus within and between hosts, tissue pathology, immune control mechanisms, and the response to treatment with promising antiviral drugs.

Plastic baby feeding bottles shed microplastic particles, say researchers

Rss Feed - Wed, 10/21/2020 - 09:15
This new study from researchers at Environmental Engineering, Trinity College Dublin, and the Medical University of Vienna shows that an average of 1 million microplastic particles per day are consumed by infants drinking from these feeding bottles. The study results are published in the latest issue of the journal Nature Food.

Novel theory illuminates the impact of environment on human health

Rss Feed - Wed, 10/21/2020 - 07:52
Researchers at Mount Sinai have proposed a groundbreaking new way to study the interaction between complex biological systems in the body and the environment.

NIH awards $1.6 million for research on hormonal control of HIV latency

Rss Feed - Wed, 10/21/2020 - 07:37
The National Institutes of Health has awarded $1.6 million to researchers at the George Washington University School of Medicine and Health Sciences for research on hormonal control of HIV latency.

Researchers explore effect of temperature on molecular structure of SARS-CoV-2 spike

Rss Feed - Wed, 10/21/2020 - 07:24
Didac Martí et al., from the Polytechnic University of Catalonia, in a recent bioRxiv preprint research paper, explore the effect of the temperature on the molecular structure of the SARS-CoV-2 spike glycoprotein. The study specifically focuses on the spike glycoprotein's molecular structural integrity at different temperatures (within 25 ºC and 100 ºC) using atomistic computer simulations.

Scientists discover mechanism linking gum disease to inflammatory conditions

Rss Feed - Wed, 10/21/2020 - 07:18
The link between periodontal (gum) disease and other inflammatory conditions such as heart disease and diabetes has long been established, but the mechanism behind that association has, until now, remained a mystery.

Conflicting evidence on potential benefit, negative outcomes of hip and knee steroid injections

Rss Feed - Wed, 10/21/2020 - 07:02
Osteoarthritis of the hip and knee is among the most common joint disorders. A frequently performed treatment for osteoarthritis and other joint related pain syndromes are IACS, yet there is conflicting evidence on their potential benefit and possible negative outcomes following such injections.

New fluid dynamics model for infectious droplets shows distancing and masks are not enough

Rss Feed - Wed, 10/21/2020 - 06:46
Wear a mask, keep your distance, avoid crowds - these are the common recommendations to contain the COVID-19 epidemic. However, the scientific foundations on which these recommendations are based are decades old and no longer reflect the current state of knowledge.

3D imaging of SARS-CoV-2 infection in ferrets using light sheet microscopy

Rss Feed - Wed, 10/21/2020 - 06:34
Researchers from the Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health demonstrate the ability to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in 3D tissue samples in ferrets. This will allow the detection of infection patterns in tissues and their interrelations.

UC study shows how tobacco use impacts patients with kidney cancer

Rss Feed - Wed, 10/21/2020 - 06:26
Researchers at the University of Cincinnati have identified new clues into ways tobacco use impacts patients with kidney cancer.

New vaccine targeting toxic Aβ may offer clinical benefit in treating Alzheimer's disease

Rss Feed - Wed, 10/21/2020 - 06:20
Our immune system's capacity to mount a well-regulated defense against foreign substances, including toxins, weakens with age and makes vaccines less effective in people over age 65.

Mortality rates higher for U.S. working-age residents living in rural areas

Rss Feed - Wed, 10/21/2020 - 06:11
A recent study by Syracuse University sociology professor Shannon Monnat shows that mortality rates are higher for U.S. working-age residents who live in rural areas instead of metro areas, and the gap is getting wider.

Engineered decoy receptor could protect against coronaviruses

Rss Feed - Wed, 10/21/2020 - 06:09
Researchers in the United States have shown that an engineered soluble decoy receptor tightly binds the spike protein of severe acute respiratory syndrome (SARS)-associated viruses. This could potentially provide protection against zoonotic betacoronaviruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic.

Researchers explore new method to monitor the effectiveness of HIV treatment at home

Rss Feed - Wed, 10/21/2020 - 06:04
Development of a new method to monitor the effectiveness of human immunodeficiency virus (HIV) treatment at home instead of in hospitals is underway by Penn State researchers.

Precision epidemiology could help explain variability in COVID-19 symptoms

Rss Feed - Wed, 10/21/2020 - 05:53
Researchers from National Taiwan University have presented a multi-omics view of how mutations in angiotensin-converting enzyme 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2) affect infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and progression of coronaviruses disease 2019 (COVID-19).

Mammography screening is efficient also for women over the age of 70

Rss Feed - Wed, 10/21/2020 - 05:52
Mammography, which is an x-ray picture of the breast, is efficient also for women over the age of 70. For women invited to regular mammography screening over the age of 70, the reduction in mortality rate was significant. This according to a vast new study from Sweden.