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Researchers apply deep learning algorithm to CT to produce spectral images

Rss Feed - Tue, 10/20/2020 - 11:59
Bioimaging technologies are the eyes that allow doctors to see inside the body in order to diagnose, treat, and monitor disease.

Study: Impact of earlier diagnosis in focal epilepsy goes beyond timely treatment

Rss Feed - Tue, 10/20/2020 - 11:55
Having subtler symptoms, a form of epilepsy that affects only one part of the brain often goes undiagnosed long enough to cause unexpected seizures that contribute to car crashes, a new study finds.

Androgen deprivation strategies could help mitigate SARS-CoV-2 infection

Rss Feed - Tue, 10/20/2020 - 11:53
Since the beginning of the COVID-19 pandemic, researchers have noted that women are generally less severely affected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This has led to the exploration into estrogen and androgens' role in the hyperinflammatory clinical phenotypes of COVID-19. A recent study published on the preprint server bioRxiv shows that drugs targeting androgens and TMPRSS2 inhibitors may potentially combat the pandemic.

Study reports children with chronic kidney disease may spend more time in hospital

Rss Feed - Tue, 10/20/2020 - 11:46
Chronically ill children with kidney disease may spend more time in the hospital, incur larger health care costs, and have a higher risk of death compared to pediatric patients hospitalized for other chronic conditions, a new study suggests.

Study shows concerning levels of COVID-19 vaccine hesitancy

Rss Feed - Tue, 10/20/2020 - 11:02
More than a third of people (34%) in Turkey and one sixth of people (17%) in the UK are 'hesitant' about a COVID-19 vaccine, according to a study by UCL and Dokuz Eylul University in Turkey.

New research finds marked impact of COVID-19 on osteoporosis management

Rss Feed - Tue, 10/20/2020 - 10:57
A new study published prior to World Osteoporosis Day finds that the COVID-19 pandemic, which has severely affected management of non-communicable diseases, is markedly impacting the management of osteoporosis as judged by access to online FRAX fracture risk assessments.

Chip-based technology can create new options for ultrasound therapy with high resolution and intensity

Rss Feed - Tue, 10/20/2020 - 10:50
A chip-based technology that generates sound profiles with high resolution and intensity could create new options for ultrasound therapy, which would become more effective and easier.

New model of human brain networks sheds light on how the brain functions

Rss Feed - Tue, 10/20/2020 - 10:33
A team of Indiana University neuroscientists has built a new model of human brain networks that sheds light on how the brain functions.

New inhaled treatment may lead to self-administered therapy for COVID-19

Rss Feed - Tue, 10/20/2020 - 10:26
An inhaled treatment against the SARS-CoV-2 virus may lead to a future self-administered therapy for COVID-19, the pandemic that has killed more than 1 million people worldwide.

The connection between severe COVID-19 and white blood cell counts

Rss Feed - Tue, 10/20/2020 - 09:18
However, in other research, white blood cells' exact roles and subtypes in severe COVID-19 are still unclear. The team writes, "It is unknown if blood cell counts before infection are associated with the risk of developing severe COVID-19." They explained that the numbers of these cell types could be influenced by several factors such as age, gender, disease status, and medications.

Adult stem cell-based lung organoid models emulate host immune response in fatal COVID-19

Rss Feed - Tue, 10/20/2020 - 08:34
Recently, a team of researchers from the University of California San Diego and The Scripps Research Institute, CA, USA, showed that an integrated stem cell-based disease modeling and computational approach is crucial for simulating the host immune response in fatal COVID-19 patients.

Molecular simulations reveal detailed structure and dynamics of SARS-CoV-2 spike protein

Rss Feed - Tue, 10/20/2020 - 08:17
Recently, researchers reported a study in which they analyzed the structure and dynamics of the spike protein using multiple molecular dynamic simulations. Their study is published on the preprint server bioRxiv.

Promising interim results for Sinopharm's inactivated whole-virion SARS-CoV-2 vaccine

Rss Feed - Tue, 10/20/2020 - 07:56
The COVID-19 pandemic has led to intensive scientific efforts to bring about an effective vaccine for global distribution. Many different vaccine design approaches are underway. A recent study published in the journal The Lancet Infectious Diseases in October 2020 reports a potentially successful inactivated virus vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Researchers provides new evidence that fear and anxiety reflect overlapping brain circuits

Rss Feed - Tue, 10/20/2020 - 07:40
Anxiety, the most common family of mental illnesses in the U.S., has been pushed to epic new heights by the COVID-19 pandemic, with the Centers for Disease Control and Prevention estimating that nearly 1 in 3 U.S. adults and a staggering 41% of people ages 18-29 experienced clinically significant anxiety symptoms in late August.

Design of an mRNA SARS-CoV-2 vaccine encapsulated in lipid nanoparticles

Rss Feed - Tue, 10/20/2020 - 07:35
Now, a new study presented on the preprint server bioRxiv in October 2020 describes the efficient design of an mRNA vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), based on the use of the viral receptor-binding domain (RBD) mRNA encapsulated in lipid nanoparticles (LNP).

Study: More intervention hours are not necessarily better for toddlers with autism

Rss Feed - Tue, 10/20/2020 - 07:35
A multisite study led by UC Davis Health found that two prominent early intervention models for autism had a similar impact.

Study points out key variations in hospice transitions and experiences

Rss Feed - Tue, 10/20/2020 - 07:17
Terminally ill patients referred to hospice care from a hospital setting tend to be on hospice for shorter periods than those who enter hospice while living at home or in a residential care facility.

Scientists find striking acceleration in medieval plague transmission over 300 years

Rss Feed - Tue, 10/20/2020 - 07:04
McMaster University researchers who analyzed thousands of documents covering a 300-year span of plague outbreaks in London, England, have estimated that the disease spread four times faster in the 17th century than it had in the 14th century.

Antigenic imprinting of sarbecovirus

Rss Feed - Tue, 10/20/2020 - 07:00
A recent study published on the preprint server bioRxiv* in October 2020 shows that the design of a vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) must consider the prior history of exposure to coronaviruses since these affect the antibody response to the virus.

Study finds dramatic increase in the use of non-invasive ventilation

Rss Feed - Tue, 10/20/2020 - 06:51
More research is needed before a less invasive form of ventilation is used near the end of life for patients who have cancer and dementia, recommends the authors of a scientific paper published in JAMA Internal Medicine.