Epidemiology of Postmenopausal Osteoporosis and Related Risk Factors in Female Residents of Tashkent and Namangan (Republic of Uzbekistan)

EPIDEMIOLOGY
S. I. Ismailov, L.S. Abboskhodjaeva, N.M. Alikhanova

Center for the Scientific and Clinical Study of Endocrinology, Uzbekistan Public Health Ministry; Tashkent, Uzbekistan

*Corresponding author: Prof.  Said I. Ismailov, PhD, Scd. Director of the Center for the Scientific and Clinical Study of Endocrinology, Tashkent, Uzbekistan E-mail: ismailov.said@list.ru

Published: June 25, 2015. DOI: 10.21103/Article5(2)_Ep1

Abstract: 

Our epidemiological survey is the first step in studying prevalence and risk factors of postmenopausal osteoporosis (PMO) in the Republic of Uzbekistan, aiming at development of early preventive and therapeutic measures to reduce osteoporosis-associated fractures.

Methods: We screened 1378 postmenopausal female residents of Tashkent and Namangan, two cities with the largest populations in Uzbekistan, aged from 50 to 80. The duration of the postmenopausal period was ≥1 year.

Results: According to our data, the prevalence of osteoporosis in different regions of Uzbekistan varies widely (33.5% and 51.1% in Tashkent and Namangan, respectively). The prevalence of osteoporosis increases with age from 25.6% (50 to 59 years) to 51.3% (in >70 age group) in Tashkent and from 44.0% to 80.0% in the same age groups in Namangan.

There were significantly more women in Namangan with body mass <57kg than in Tashkent (OR 2.44; 95%CI 1.72-3.46; P<0.00001). We found that the number of women doing physical exercises in Tashkent was 2 times more than in Namangan (65.5% versus 36.1%, OR 3.36; 95%CI 2.64-4.27; P<0.0001).

Conclusion: Our research shows that osteoporosis is widely spread among women above 50 living in two big densely populated cities of Uzbekistan (Tashkent and Namangan). Low body mass and irregular physical activity, fracture history, and duration of menopause are the factors of risk in the studied cohorts of women. 

Keywords: 
menopause; risk factors; osteopenia; osteoporosis.
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Int J Biomed. 2015; 5(2):95-99. © 2015 International Medical Research and Development Corporation. All rights reserved.