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Drug repurposing breakthrough: varespladib curbs snakebite-induced necrosis
Researchers discovered that venom toxins from African spitting cobras cause severe dermonecrosis, highlighting the need for targeted treatments like the repurposed drug varespladib.
Breakthrough vaccine strategy guides the immune system to generate HIV neutralizing antibodies
A team led by the Duke Human Vaccine Institute (DHVI) has developed a vaccine approach that works like a GPS, guiding the immune system through the specific steps to make broadly neutralizing antibodies against HIV.
Discrimination linked to accelerated biological aging
Discrimination may speed up the biological processes of aging, according to a new study led by researchers at the NYU School of Global Public Health.
Innovative "smart" contact lens may revolutionize glaucoma detection and monitoring
Most people with early-stage glaucoma don't know they have it, even though early treatment is key to reducing vision loss.
Prenatal exposure to bisphenol and phthalate linked to increased child obesity, study finds
Researchers found links between higher prenatal exposure to bisphenols and high-molecular-weight phthalates with increased child weight and BMI from birth to age four in a New York cohort study.
Research exposes water, sanitation inaccessibility for homeless and drug users during the pandemic
A defining development of the 20th century that changed the course of public health was when governments around the world improved access to safe water, sanitation and hygiene.
Common drivers of high-performing public health programs revealed
The highest performing countries across public health outcomes share many drivers that contribute to their success.
Researchers create the largest 3D reconstruction of human brain fragment
A cubic millimeter of brain tissue may not sound like much. But considering that tiny square contains 57,000 cells, 230 millimeters of blood vessels, and 150 million synapses, all amounting to 1,400 terabytes of data, Harvard and Google researchers have just accomplished something enormous.
African regions at risk for malaria transmission may decline more than previously expected
Areas at risk for malaria transmission in Africa may decline more than previously expected because of climate change in the 21st century, suggests an ensemble of environmental and hydrologic models.
Combination immunotherapy treatment enhances immune response for people with malignant gliomas
Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have pinpointed a combination immunotherapy treatment that enhances the immune response for people with malignant gliomas, an aggressive type of brain tumor that is fast growing and difficult to treat.
Experts identify highly drug-resistant infections from stem cell treatments In Mexico
Experts in mycobacterial diseases at National Jewish Health, in collaboration with local health departments and the Centers for Disease Control and Prevention (CDC), are investigating a potential outbreak of a highly drug-resistant mycobacterium (germ) after U.S. patients who traveled to Mexico for stem cell injections became sick.
Ketogenic diet a potential therapy for autism by reshaping gut bacteria and brain inflammation
Modified ketogenic diet modulates gut microbiome, inflammatory markers, and brain-related miRNAs in autistic children, correlating with improved behavioral symptoms. The diet increases beneficial gut bacteria and reduces inflammatory cytokines and BDNF levels.
Researchers unveil digital 'alcohol twin' to predict drinking risks and guide personalized interventions
Digital twin model simulates real-life alcohol consumption patterns and links them to long-term biomarkers, aiding eHealth strategies to curb dangerous drinking habits. The model captures complex physiological interactions between food, beverages, and alcohol metabolism.
Study uncovers alcohol's damaging effects on brain cells through oxidative stress
Alcohol exposure leads to accumulation of oxidatively damaged proteins in neuronal cells. Differentiated cells are more susceptible to alcohol-induced oxidative protein damage despite higher resistance to cytotoxicity.
Study reveals altered protein rhythms linked to metabolic disorders in night shift workers
Just a few days on a night shift schedule throws off protein rhythms related to blood glucose regulation, energy metabolism and inflammation, processes that can influence the development of chronic metabolic conditions.
UT Health San Antonio leads effort for developing oral vaccine against chlamydia
The study of a novel oral vaccine that could protect against chlamydia infection has been awarded approximately $11 million in National Institutes of Health funding over five years through a cooperative agreements research project grant, known as a U01 grant.
Ensemble deep learning models enhance early diagnosis of Alzheimer's disease using neuroimaging data
The developments in ensemble deep learning (EDL) models used to characterize and estimate AD.
Relaxation interventions can be offered to lactating parents who would like to improve milk supply and increase well-being
A recent study in JAMA Pediatrics explored the utility of relaxation therapy in increasing milk production in human mothers.
Increase in sedentary time from childhood causes progressing heart enlargement, new study shows
A recent study investigated whether sedentary time (ST), light-intensity physical activity (LPA), and moderate-to-vigorous-intensity physical activity (MVPA) during childhood and young adulthood influence cardiac structure and function.
Placental DNA methylation patterns altered by pregnancy air pollution exposure, research reveals
The relationship between prenatal air pollutant exposure concentrations and changes in placental deoxyribonucleic acid (DNA) methylation.