Evaluation of Liver in Type 2 Diabetes Mellitus Using Unenhanced Computed Tomography

Huda Osama, Afraa Siddig, Awadia Gareeballah, Moawia Gameraddin, Hanady Elyas Osman

International Journal of Biomedicine. 2020;10(4):402-406.
DOI: 10.21103/Article10(4)_OA14
Originally published December 10, 2020


Background: Chronic liver disease occurs due to different etiologies. Most diabetic patients are unaware that the effective control of hyperglycemia might reduce complications and mortality rates. Fatty liver disease is considered a risk factor of hepatic cirrhosis and cancers.
Methods and Results: We conducted a case-control study to assess the impact of type 2 diabetes mellitus (T2DM) on the liver using a CT scan. A total of 100 patients with T2DM and 96 non-diabetic patients as a control group were selected using a convenient sampling method.
There was a significant difference in liver attenuation in diabetic and control groups. The CT attenuation values of the liver, pancreas, and spleen were significantly lower in patients with T2DM than in non-diabetics (P<0.001). There was a significant negative correlation between the duration of T2DM and CT attenuation of the liver, pancreas, and spleen (P<0.01).
Conclusion: The CT attenuation of the liver was significantly lower in T2DM than in the non-diabetic patients, and liver attenuation decreased as the duration of T2DM increased.

diabetes mellitus • nonalcoholic fatty liver disease • liver attenuation • unenhanced computed tomography
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Received October 10, 2020.
Accepted November 10, 2020.
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