Study on the Healing Effect of Syringaresinol β-D-Monoglucoside

DRUG DEVELOPMENT AND RATIONAL USE OF DRUGS
Аrkadiy А. Semenov, PhD, SD¹'²*; Andrey G. Enikeev, PhD²; Valentina B. Khobrakova, PhD, ScD³ ; Yanina G. Razuvayeva, PhD³ ; Sergey М. Nikolayev, PhD, ScD³

¹Irkutsk State Technical University, Irkutsk;  ²Siberian Institute of Plant Physiology and Biochemistry, SB RAS, Irkutsk; ³Institute of General and Experimental Biology, SB RAS, Ulan-Ude; Russian Federation

*Corresponding author: Arkadiy A. Semenov, PhD, ScD, corresponding member of RAS. Siberian Institute of Plant Physiology and Biochemistry SB RAS, 132 Lermontov street, Irkutsk, 664033, Russian Federation. Tel: (3952)426676. E-mail: laps1936@mail.ru

Published: December 25, 2013 

Abstract: 

The present study focused on the impact of lignane syringaresinol beta-D-monoglucoside (substance 1) on the healing process of the linear and planar wounds in white male Wistar rats, with a body mass ranging between 180 and 200g. This substance was found to contribute towards quicker healing of the wound damage, when compared with solcoseryl. Thus, the solidity of the cicatrix with the substance 1 injection exceeded that which resulted from the solcoseryl injection. Substance 1 was also found to exert an anti-inflammatory effect. However, in the intensity and timing of inflammatory stage changes it was analogous to the solcoseryl impact.

Keywords: 
wounds; healing; syringaresinol beta--D-monoglucoside; solcoseryl.
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Int J Biomed. 2013; 3(4):287-290. © 2013 International Medical Research and Development Corporation. All rights reserved.