Biomarkers of Liver in Patients with Chronic Pancreatitis Associated with Metabolic Syndrome

Gulchehra R. Yuldasheva, PhD¹*; Feruza I. Khamrabaeva, PhD, ScD¹; Abdugafur A. Khadzhimetov, PhD, ScD²

¹Tashkent Institute of Postgraduate Medical Education; ²Tashkent Medical Academy; Tashkent, Uzbekistan

*Corresponding author: Gulchehra R. Yuldasheva, PhD.  Tashkent Institute of Postgraduate Medical Education. Tashkent, Uzbekistan.  E-mail:

Published: March 25, 2014.


A study of the carbohydrate and lipid metabolism, as well as the leptin level was conducted in 69 patients with chronic pancreatitis (CP) associated with the metabolic syndrome (MS). The results revealed significant changes in the serum parameters studied in patients with CP and MS. The authors concluded that in such patients, the irregularities in the glucose-insulin homeostasis are evident, not only due to hormonal disorders, but also due to impairment cellular metabolism, against the backdrop of excessive free fatty acid (FFA) levels.

chronic pancreatitis; metabolic syndrome; carbohydrate and lipid metabolism.
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Int J Biomed. 2014; 4(1):23-25. © 2014 International Medical Research and Development Corporation. All rights reserved.