Role of Nerve Growth Factor in Assessing the Severity of Clinical Manifestations and Outcomes of Perinatal CNS Lesions in Infants

ORIGINAL ARTICLE
Olga N. Krasnorutskaya, PhD*; Daniel Yu. Bugrimov, PhD; Anna A. Zuykova, PhD, ScD; Alexander N. Pashkov, PhD, ScD; Julia A. Kotova, PhD; Natalia V. Strakhova, PhD; Irina S. Dobrynina, PhD

Voronezh State Medical University named after N.N. Burdenko; Voronezh, the Russian Federation

*Corresponding author: Olga N. Krasnorutskaya, PhD. Voronezh State Medical University named after N.N. Burdenko. Voronezh, the Russian Federation. E-mail: onkrasnorutckaja@rambler.ru

Published: December 16, 2016.  DOI: 10.21103/Article6(4)_OA5

Abstract: 

The purpose of our research was to analyze the association between the serum beta-NGF level and the severity of neurological deficit (ND) in children in the first year of life. Our results suggest a possible functional link between the low level of NGF and the development of severe ND. The obtained results allow us to consider the serum beta-NGF level as a useful marker of the ND severity in young children.

Keywords: 
nerve growth factor, neurological deficit, central nervous system, perinatal lesions.
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Int J Biomed. 2016;6(4):276-278. © 2016 International Medical Research and Development Corporation. All rights reserved.