Faculty of biomedical engineering, Czech Technical University; Prague, Czech Republic
*Corresponding author: Mariia Simonova, Faculty of biomedical engineering, Czech Technical University; Prague, Czech Republic. E-mail: firstname.lastname@example.org
Published: December 16, 2016. DOI: 10.21103/Article6(4)_CR1
The present study investigates the possibility of detecting changes in cerebral oxygenation and consequently of intraventricular hemorrhage (IVH) in preterm children using paired data from the NIRS-monitor and the patient vital signs monitor. During the study, one patient's data were analyzed. The patient was born at the gestational age of 25+6 weeks. He was monitored for a period of 72 hours. IVH was first detected by the ultrasound diagnostics in 1000 minutes after birth. Analysis of the paired data showed that HR is not a useful IVH indicator. Comparison of the regional cerebral (cSrO2) and peripheral blood oxygen saturation (SpO2) changes and cerebral fractional oxygen extraction (OEF) with its second derivative represents a more beneficial method. It shows the tissue oxygen absorption changing (ie, periods of great change in hemodynamic, at the beginning or end of IVH). By comparing the calculated results and the medical records of the IVH course, it can be argued that this method can be efficiently used to determine the start and end of the bleeding into the brain ventricles.
- Preterm birth: Fact sheet N°363. World Health Organization: Media centre, 2015. http://www.who.int/mediacentre/factsheets/fs363/en/
- Al-Abdi SY, Al-Aamri MA. A Systematic Review and Meta-analysis of the Timing of Early Intraventricular Hemorrhage in Preterm Neonates: Clinical and Research Implications. J Clin Neonatol. 2014;3(2):76-88.
- Jezová M, Múcková K, Soucek O, Feit J, Vlasín P. Hypertext atlas of fetal and neonatal pathology. Diagn Pathol. 2008;3 Suppl 1:S9. doi: 10.1186/1746-1596-3-S1-S9.
- Leviton A, Kuban K, Paneth N. Intraventricular haemorrhage grading scheme: time to abandon? Acta Paediatr. 2007;96(9):1254-6.
- Sood BG, McLaughlin K2, Cortez J3. Near-infrared spectroscopy: applications in neonates. Semin Fetal Neonatal Med. 2015;20(3):164-72.
- Boushel R, Langberg H, Olesen J, Gonzales-Alonzo J, Bülow J, Kjaer M. Monitoring tissue oxygen availability with near infrared spectroscopy (NIRS) in health and disease. Scand J Med Sci Sports. 2001;11(4):213-22.
- Bozkurt A, Rosen A, Rosen H, Onaral. A portable near infrared spectroscopy system for bedside monitoring of newborn brain. Biomed Eng Online. 2005;4:29.
- Zhang Y, Chan GS, Tracy MB, Lee QY, Hinder M, Savkin AV, Lovell NH. Cerebral near-infrared spectroscopy analysis in preterm infants with intraventricular hemorrhage. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:1937-40.
- Kaufman J, Almodovar MC, Zuk J, Friesen RH. Pediatr Crit Care Med. 2008;9(1):62-8. Correlation of abdominal site near-infrared spectroscopy with gastric tonometry in infants following surgery for congenital heart disease.
The fully formatted PDF version is available.
Int J Biomed. 2016;6(4):290-293. © 2016 International Medical Research and Development Corporation. All rights reserved.