Impact of Metabolic Syndrome Components on Asthma Control and Life Quality of Patients

Andrey V. Budnevsky, PhD, ScD; Ludmila V. Tribuntceva, PhD; Svetlana A. Kozhevnikova, PhD; Evgeniy S. Ovsyannikov, PhD

Voronezh State Medical University named after N.N. Burdenko, Voronezh, the Russian Federation

*Corresponding author: Evgeniy S. Ovsyannikov, PhD. Department of faculty therapy, Voronezh State Medical University named after N.N. Burdenko. Voronezh, Russia. E-mail: ovses@yandex.ru

Published: March 15, 2018.  doi: 10.21103/Article8(1)_OA4

Abstract: 

The purpose of this study was to assess the characteristics of the clinical course of asthma in patients with metabolic syndrome (MetS) and to analyze the influence of the MetS components on the course of asthma, control of asthma symptoms, and the the quality of life (QL) of  patients with asthma.
Materials and Methods: We examined 95 asthma patients aged from 18 to 60 years. The patients were divided into 2 groups. Group 1 included 35 patients without MetS (24/68.6% women and 11/31.4% men; mean age, 49.81±0.77 years), and Group 2 included 60 patients with MetS(45/75.0% women and 15/25.0% men; mean age, 49.82±0.77 years).
Results: The patients with asthma and MetS have a more severe clinical course of asthma, with frequent exacerbations and uncontrolled asthma symptoms, low spirometry results and a low level of QL.

Keywords: 
asthma ● metabolic syndrome ● uncontrolled asthma symptoms ● quality of life
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International Journal of Biomedicine. 2018;8(1):33-36. ©2018 International Medical Research and Development Corporation. All rights reserved.