Synchronization of Wave Flows of Arterial and Venous Blood with Phases of the Cardiac Cycle in Norm: Part 1
International Journal of Biomedicine. 2018;8(2):123-128.
Originally published June 15, 2018
Hemodynamic indices studied in practically healthy people were obtained by catheterization in various vascular areas: the chambers of the heart (left ventricle, right ventricle, left atrium, right atrium, coronary sinus), pulmonary trunk, aorta, inferior vena cava, superior vena cava, right hepatic vein, and sigmoid sinus. In the investigated areas, using the mean values of the hemodynamic parameters, we constructed graphics of the "curves" of the central, arterial, and venous pressure, synchronized with each other and ECG. Separation of a sequential scheme of the cardiac cycle (CC) into the phases indicated in the text allowed us to determine (on the superimposed curves) the points of intersection (equal pressure values—zeroing of the pressure gradients) of the hemodynamic and wave processes simultaneously occurring in various parts of the vascular bed (including those remote from the heart). As a result of the analysis, we propose a scheme (which is key to periodization of the CC phases) of the sequences of zones of temporal equalization of pressure (a rapidly acting matrix of pressure equalization points) initiated by the systole of the three-chamber ventricular block, part of which is the trigger mechanism for the next phase of CC.
- Gebel GYa, Utkin VN, Dasaev AN, Kruglov AG, Smirnov EP, Golostenova LM, et al. Pressure of blood and gases in human vessels (coronary sinus, pulmonary artery, and aortic bulb). Proceedings of the 9th Plenum of the board of anesthesiologists and resuscitators of Russia. M.,1993:76-79 [Article in Russian].
- Gebel GYa, Utkin VN, Dasaev AN, Kruglov AG, Golostenova LM, Bagdatyev VE, et al. Pressure (total, gas and hemodynamic) in the vessels of the human heart in the "norm" - coronary sinus, pulmonary artery, aortic bulb. Symposium dedicated to the clinic, diagnosis, and treatment in Russia. M., 1993:25-29. [Article in Russian].
- Gebel GYa, Kruglov AG, Utkin VN, Bagdatyev VE, Dasaev AN, Golostenova LM. [On the role of the coronary sinus of the human heart in the norm (regulation of a number of functions to the issue of synchronization in the circulatory system)]. Proceedings of the 10th Conference on Space Biology and Aerospace Medicine. M., 1994:56-57. [Article in Russian].
- Kruglov AG, Gebel GY, Vasilyev AY. Impact of Intra-Extracranial Hemodynamics on Cerebral Ischemia by Arterial Hypertension (Part 2). International Journal of Biomedicine. 2012; 2(2):96-101. Google Scholar
- Kruglov AG, Utkin VN, Vasilyev AY, Sherman V. Human Homeostatic Control in Norm. International Journal of Biomedicine. 2016;6(3):184-9. Google Scholar
- Kruglov AG, Utkin VN, Vasilyev AY. The Role of Integrated Gas Compounds in Regulation of Gas Homeostasis in the Norm”. International Journal of Biomedicine. 2017; 7(3):185-191. Google Scholar
- Van Rijk-Zwikker GL, Delemare BJ, Huesmans HS. Mitral valve anatomy and morphology: relevance to mitral valve replacement and valve reconstruction”. J Cardiol Surg. 1994;9(2 Suppl):255-61. PubMed
- Sudakov KV. Physiology: Foundations and Functional Systems. M.: Medicine; 2000. [In Russian].
- Lightfoot A. Transport phenomena in live systems. Biomedical aspects of momentum and mass transport. M.: Mir, 1977. [In Russian]
- Guyton AC and Hall JE, eds. Textbook of Medical Physiology. 10th ed. Philadelphia, PA: W.B. Saunders Company, 2000.
Received February 28, 2018.
Accepted March 18, 2018.
©2018 International Medical Research and Development Corporation.