Metabolic Syndrome in Indigenous Minorities of the North of Yakutia

Sargylana I. Sofronova, Anna N. Romanova, Vyacheslav M. Nikolaev, Lubov D. Olesova, Nadezhda K. Chirikova

International Journal of Biomedicine. 2018;8(3):232-234.   
DOI: 10.21103/Article8(3)_OA13
Originally published September 15, 2018  


The aim of our research was to study the prevalence of metabolic syndrome (MetS) in the North of Yakutia. The study was conducted under expeditionary conditions in the northern regions of Yakutia in the places where the indigenous peoples of the North live. A total of 686 people aged between 20 and 70 were examined in 4 districts: Anabarsky (Anabar), Nizhnekolymsky (Lower Kolyma), Verkhnekolymsky (Upper Kolyma), and Tomponsky (Tompo). In all regions, there was a high prevalence of hypertension, with the highest frequency in the Anabarsky District. The greatest frequency of MetS was found in the Evenks (56.7%) and the lowest in the Chukchi (20%). Women had higher MetS frequency than men, and differences between men and women are statistically significant, with the highest frequency in Evenks women (61.1%).

indigenous minorities • abdominal obesity • arterial hypertension • metabolic syndrome
  1. Health in the Republic Sakha (Yakutia):  State Statistics of Sakha Republic (Yakutia).Yakutsk, 2016.
  2. O'Neill S, O'Driscoll L. Metabolic syndrome: a closer look at the growing epidemic and its associated pathologies. Obes Rev. 2015;16(1):1–12. doi: 10.1111/obr.12229. PubMed
  3. Kaur J. A comprehensive review on metabolic syndrome. Cardiol Res Pract. 2014;2014:943162. doi: 10.1155/2014/943162. PubMed
  4. Beltran-Sanchez H, Harhay MO, Harhay MM, McElligott S. Prevalence and trends of metabolic syndrome in the adult U.S. population, 1999-2010. J Am Coll Cardiol. 2013;62(8):697-703. doi: 10.1016/j.jacc.2013.05.064. PubMed
  5. DECODA Study Group. Prevalence of the metabolic syndrome in populations of Asian origin. Comparison of the IDF definition with the NCEP definition. Diabetes Res Clin Pract. 2007;76(1):57–67. PubMed
  6. Assmann G, Guerra R, Fox G, Cullen P, Schulte H, Willett D, Grundy SM. Harmonizing the definition of the metabolic syndrome: comparison of the criteria of the Adult Treatment Panel III and the International Diabetes Federation in United States American and European populations. Am J Cardiol. 2007;99(4):541-8. PubMed
  7. Ford ES. Prevalence of the metabolic syndrome in US populations. Endocrinol Metab Clin North Am. 2004;33(2):333–50. PubMed
  8. Ford ES. Risks for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome: a summary of the evidence. Diabetes Care. 2005;28(7):1769-78. PubMed
  9. Gami AS, Witt BJ, Howard DE, Erwin PJ, Gami LA, Somers VK, Montori VM. Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and meta-analysis of longitudinal studies. J Am Coll Cardiol. 2007;49(4):403-14. PubMed
  10. Ametov AS. [Obesity – epidemic XXI century].  Ter Arkh. 2002;74(10):5-7. [Article in Russian]. PubMed
  11. Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, et al.; American Heart Association; National Heart, Lung, and Blood Institute. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation. 2005;112(17):2735-52. PubMed
  12. Zimmet P, Shaw J, Alberti KG. Preventing Type 2 diabetes and the dysmetabolic syndrome in the real world: a realistic view. Diabet Med. 2003;20(9):693-702. PubMed
  13. Khamnagadaev II. Prevalence of arterial hypertension, ischemic heart disease and their risk factors in the rural indigenous population of the North and Central Siberia. Abstract of ScD Thesis. Tomsk, 2008. [In Russian].
  14. Metabolic syndrome diagnostics and treatment. Compilation of national recommendations. Moscow: Silicea-Poligraf Publishers; 2009:106–143. [In Russian].
  15. IDF Consensus Worldwide Definition of the Metabolic Syndrome, 2006. Available from:

Download Article
Received June 14, 2018.
Accepted July 3, 2018.
©2018 International Medical Research and Development Corporation.