Treatment of Acute Venous Thromboses and Pulmonary Embolism during Pregnancy

Mikhail M. Vinokurov, Anton A. Yakovlev, Vasily P. Ignatiev, Natalia I. Douglas, Gennady A. Palshin, Iana G. Rad, Innokenty D. Ushnitsky

International Journal of Biomedicine. 2018;8(3):244-246.   
DOI: 10.21103/Article8(3)_ShC1
Originally published September 15, 2018  


The aim of the study was to improve the results of the treatment of acute ascending varicothrombosis, deep vein thrombosis (DVT) and pulmonary embolism (PE) during pregnancy and the postpartum period. The study included 22 pregnant women aged between 20 and 41 years in different periods of pregnancy and in the early postpartum period, with acute thrombosis of deep and superficial veins of the lower extremities complicated by PE. All of the generally accepted methods for treatment of DVT, varicothrombophlebitis and PE were applied. In 16(72.8%) pregnant women with DVT of the lower limbs, in the absence of free-floating thrombus, conservative treatment was effective; an IVC filter was placed in only 1 patient. Combined phlebectomies of the great saphenous vein with thrombosed tributaries were performed in 4(18.8%) patients with ascending varicothrombosis in the early postpartum period, resulting in early recovery and discharge from the hospital. Thrombolytic therapy in the patient with massive PE in the first trimester of pregnancy saved the life of the mother and child.

pulmonary embolism • deep vein thrombosis • pregnancy • ultrasonic duplex scanning • low molecular weight heparin

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Received June 28, 2018.
Accepted July 13, 2018.
©2018 International Medical Research and Development Corporation.