The Frequency and Neuroimaging Characteristics of Macro- and Giant Pituitary Adenomas

Yulduz M. Urmanova, Salimjon P. Sodikov, Minji Kim, Temur A. Duschanov, Shakhnoza Sh. Mukhtarova

International Journal of Biomedicine. 2019;9(1):72-74.
DOI: 10.21103/Article9(1)_ShC1
Originally published March 15, 2019


Data from 3 medical centers of Tashkent city, in which 156 patients (76 men and 80 women) with pituitary macroadenomas (PMA) and giant pituitary adenomas (GPA) were treated during 3 years (between 2015 and 2017), were retrospectively analyzed. The results of the study showed that the different variants of PMA/GPA suprasellar growth might serve as a neuroimaging marker of tumor aggressiveness, namely, supra-infra-latesellar and supra-infra-tellular growth observed in 68 (43.5%) patients, as well as invasive tumor growth in 108 (69.2%) patients. Transsphenoidal removal is a relatively safe and effective method, even in MPA and GPA with suprasellar extensions, in most of the cases.

giant pituitary adenomas • pituitary macroadenomas • magnetic resonance imaging • transsphenoidal hypophysectomy
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Received January 26, 2019.
Accepted February 26, 2019.
©2019 International Medical Research and Development Corporation.