Analyzing Trace Elements in the Structures of Glaucomatous Eyes

Elena Iomdina, Lusine Arutyunyan, Elena Khorosheva

International Journal of Biomedicine. 2019;9(1):23-25.
DOI: 10.21103/Article9(1)_OA3
Originally published March 15, 2019


Trace elements (TE) were analyzed in sclera biopsy specimens, samples of anterior chamber aqueous humor, and tear fluid of 12 patients aged between 53 and 79 years with various stages of primary open-angle glaucoma (POAG), using an atomic absorption spectrometer AS-3, inductively coupled plasma-mass spectrometer ELAN 6100-ICP-MS (Perkin-Elmer), and a Thermo Scientific plasma spectrometer iCAP-7000 (USA). Detected irregularities in the content of some TE (magnesium, iron, zinc, etc.) in anterior chamber aqueous humor of POAG patients may be a serious pathogenetic factor that violates the viscosity, and hence, the hydrodynamics, of intraocular fluid. An imbalance of TE in the tissues and media of glaucomatous eyes can contribute to the development of glaucomatous damage.

sclera • anterior chamber • aqueous humor • trace elements • glaucoma
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Received January 25, 2019.
Accepted February 13, 2019.
©2019 International Medical Research and Development Corporation.