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New study advocates for de-escalating breast cancer surgery in women aged 55 and older
Surgery involving sentinel lymph node biopsy for middle-aged women with estrogen receptor-positive (ER+) breast cancer may do more harm than good, according to a new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers.
Study reveals ferroptosis as a major driver of severe COVID-19 lung damage
Ferroptosis, an iron-dependent cell death mechanism, is identified as a key factor in severe COVID-19 lung disease, suggesting potential new therapeutic targets.
Cognitive decline predicts driving cessation in seniors
One of the thorniest decisions facing older adults is when to give up their keys and stop driving. A new study by researchers at Washington University School of Medicine in St. Louis could provide guidance in helping seniors plan ahead.
Dupilumab shows promise in cutting COPD flare-ups and boosting lung function
Dupilumab significantly reduces exacerbations and improves lung function in COPD patients with elevated eosinophil counts, confirming the efficacy of targeting type 2 inflammation.
Sharp uptick in youth using wegovy and ozempic, study reports
Public interest in weight loss drugs like Wegovy and Ozempic is surging, but national data on dispensing patterns in the United States are surprisingly scarce.
Labor epidurals linked to lower risk of severe maternal morbidity
Having an epidural during labor is associated with a marked reduction in serious complications in the first few weeks after giving birth, finds a study published by The BMJ today.
Ancient viral sequences in the human genome may contribute to psychiatric disorder susceptibility
New research led by King's College London has found that thousands of DNA sequences originating from ancient viral infections are expressed in the brain, with some contributing to susceptibility for psychiatric disorders such as schizophrenia, bipolar disorder, and depression.
UCSF to lead first long-term study of cancer among Asian Americans
UC San Francisco researchers have received $12.45 million from the National Cancer Institute (NCI) to lead the first long-term study of cancer among Asian Americans, a highly diverse yet understudied group.
100-year-old BCG vaccine protects individuals with type 1 diabetes from infectious diseases
In new research, investigators at Massachusetts General Hospital (MGH) show that the 100-year-old Bacillus Calmette-Guérin (BCG) vaccine, originally developed to prevent tuberculosis, protects individuals with type 1 diabetes from severe COVID-19 disease and other infectious diseases.
Study shows dramatic increase in daily cannabis use in the United States
Many countries around the world are considering revising cannabis policies. A new study by a researcher at Carnegie Mellon University assessed cannabis use in the United States between 1979 and 2022, finding that a growing share of cannabis consumers report daily or near-daily use and that their numbers now exceed those of daily and near-daily alcohol drinkers. T
Study reveals biological repercussions of UV-C radiation exposure from germicidal lamps
A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 9, entitled, "Germicidal lamps using UV-C radiation may pose health safety issues: a biomolecular analysis of their effects on apoptosis and senescence."
Study reveals endurance exercise's impact on the biological molecules of animals and humans
As part of an ongoing national research effort to better understand how physical activity improves health and prevents disease, seven University of Colorado Department of Medicine faculty members contributed to an article recently published in Nature, an international journal of science.
Study suggests miR-377 as potential therapeutic target for prostate cancer
A new research paper was published in Genes & Cancer on May 16, 2024, entitled, "Inhibitory effect of miR-377 on the proliferative and invasive behaviors of prostate cancer cells through the modulation of MYC mRNA via its interaction with BCL-2/Bax, PTEN, and CDK4."
Improved animal model captures full picture of periodontal disease progression
Periodontal disease, represented by periodontitis, is the leading cause of tooth loss and affects close to one in five adults worldwide.
Single-cell analysis reveals insights into immune responses during xenotransplantation
Surgical teams at NYU Langone Health performed the world's first genetically modified pig kidney transplants into a human body in September and November 2021, and then transplanted two pig hearts in the summer of 2022.
Biological similarities found between "chemo brain" and brain fog after COVID-19
Brain fog after COVID-19 is biologically similar to cognitive impairment caused by cancer chemotherapy, something doctors often refer to as "chemo brain."
Lemon verbena extract boosts sleep quality
Researchers explore the utility of lemon verbena in improving the sleep of individuals with poor sleep.
Inflammatory bowel disease associated with slightly increased risk of heart failure
Inflammatory bowel disease (IBD) is associated with a slightly increased risk of heart failure up to 20 years after diagnosis, according to a comprehensive registry study from Karolinska Institutet in Sweden published in the European Heart Journal.
Are ultraprocessed foods putting your child's heart at risk?
Associations between ultra-processed food (UPF) consumption and cardiometabolic risk factors in young children.
Substituting dairy with whole grains and olive oil lowers non-communicable disease risk
Review and meta-analysis published in Current Developments in Nutrition examined long-term dietary associations of dairy products and non-communicable diseases (NCDs), finding no significant change in NCD risk with different dairy products but identifying increased risk with red and processed meat substitutions and improved outcomes with whole grains and olive oils.