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Researchers identify risk factors for SARS-CoV-2 reinfection

Rss Feed - Fri, 04/16/2021 - 20:04
A team of scientists from the Capital Medical University and Peking University, China, has recently explored the factors responsible for the reactivation of SARS-CoV-2 infection among individuals who have recently recovered from COVID-19. The findings reveal that individuals with lower lymphocyte count or with two or fewer symptoms during the first COVID-19 episode are at higher risk of recurrent infection.

Numerous agents with anti-SARS-CoV-2 potential discovered with crystallographic screening

Rss Feed - Fri, 04/16/2021 - 19:46
An international team of researchers focused on the macrodomain part of the non-structural protein 3 (Nsp3) gene product that SARS-CoV-2 uses to overturn the host cell’s natural antiviral response. The team provided a template that can help develop novel antivirals that are direct-acting and can combat the current pandemic.

Study reveals new lineage of tuberculosis-causing bacteria in the eastern part of the continent

Rss Feed - Fri, 04/16/2021 - 19:38
Mireia Coscollá, a researcher at the Institute for Integrative Systems Biology (I2SysBio), a joint centre of the University of Valencia and the Spanish National Research Council, has led a study on the bacterium that causes tuberculosis, one of the 10 deadliest diseases in the world, which proves the existence of a new lineage.

SARS-CoV-2 can alter bone marrow macrophage (BMM)-to-osteoclast differentiation, study finds

Rss Feed - Fri, 04/16/2021 - 19:31
Now, a team of researchers in China and Australia has shown that SARS-CoV-2 infection can affect bone marrow macrophage (BMM)-to-osteoclast differentiation, which may impact the skeletal system.

Researchers identify new targets to control angiogenesis

Rss Feed - Fri, 04/16/2021 - 19:28
Angiogenesis is a process of new vessel formation that is activated both in physiological (tissue repair, reproduction, etc.) and pathological (myocardial infarction, diabetic retinopathy, cancer, etc.) conditions.

Study assesses the link between women's lifestyle and risk of recurrent pregnancy loss

Rss Feed - Fri, 04/16/2021 - 19:23
A new study has shown that underweight and overweight women are at a significantly higher risk of experiencing recurrent miscarriages compared to those of average weight.

Shift working hours out of sync with body clock linked with greater cardiovascular risk

Rss Feed - Fri, 04/16/2021 - 19:20
Working hours that deviate from an individual's natural body clock are associated with greater cardiovascular risk, according to research presented at ESC Preventive Cardiology 2021, an online scientific congress of the European Society of Cardiology (ESC).

New and more effective treatment for Pompe disease

Rss Feed - Fri, 04/16/2021 - 18:11
Rare diseases are sometimes the most difficult to treat because of a lack of research and fewer participants to study.

Rapid mRNA vaccination effectively controls SARS-CoV-2 transmission in long-term care facilities

Rss Feed - Fri, 04/16/2021 - 17:22
Vaccine rollouts all over the world are aimed at cutting short the coronavirus disease 2019 (COVID-19) pandemic by inducing antibody-mediated immunity to the virus. A new study, recently released on the medRxiv* preprint server, addresses the successful reduction in viral spread and case incidence among residents of long-term care facilities (LTCF).

COVID-19 vaccination of lactating mothers elicits specific IgA antibodies in breast milk

Rss Feed - Fri, 04/16/2021 - 17:03
A new study, released on the medRxiv* preprint server, examines the presence of SARS-CoV-2-specific IgA in human milk and its association with the protection of breastfed infants against the disease.

Curcumin nanosystems could be powerful COVID-19 therapeutics

Rss Feed - Fri, 04/16/2021 - 16:41
With new variants of SARS-CoV-2 emerging, the COVID-19 pandemic is far from over. While the global vaccine rollout has moved at an impressive speed, the search for new safe, effective, and targeted therapies is still on. Now, a new study reviews the potential for curcumin, a natural alkaloid derived from turmeric, and nanosystems to treat COVID-19.

Repurposing an existing, cheap drug into long-acting injectable therapy to treat Covid-19

Rss Feed - Fri, 04/16/2021 - 15:30
Researchers from the University of Liverpool have shown the potential of repurposing an existing and cheap drug into a long-acting injectable therapy that could be used to treat Covid-19.

Researchers evaluate the ability of visio-vestibular examination to enhance concussion diagnosis

Rss Feed - Fri, 04/16/2021 - 11:24
Early and accurate diagnosis leads to optimal recovery from concussion. Over the past year across a series of studies, the Minds Matter Concussion Program research team at Children's Hospital of Philadelphia (CHOP) has systematically evaluated the use of the visio-vestibular examination (VVE) and its ability to enhance concussion diagnosis and management.

Researchers probe intriguing interaction between sugars and the SARS-CoV-2 spike protein

Rss Feed - Fri, 04/16/2021 - 11:09
A new study posted to the bioRxiv preprint server focuses on a novel formulation of magnetization or saturation transfer. This method is developed by amalgamating theoretical and computational approaches based on a Bayesian deconvolution algorithm, which helps obtain data more accurately and determine the ligand-protein interaction.

Engaging in household chores may be beneficial for brain health in older adults

Rss Feed - Fri, 04/16/2021 - 11:08
Engaging in household chores may be beneficial for brain health in older adults. In a recent Baycrest study, older adults who spent more time on household chores showed greater brain size, which is a strong predictor of cognitive health.

Complex patterns of genetic ancestry can provide insights into genetic, environmental factors of many diseases

Rss Feed - Fri, 04/16/2021 - 11:07
The complex patterns of genetic ancestry uncovered from genomic data in health care systems can provide valuable insights into both genetic and environmental factors underlying many common and rare diseases--insights that are far more targeted and specific than those derived from traditional ethnic or racial labels like Hispanic or Black, according to a team of Mount Sinai researchers.

“Expansion Hunter” method can detect DNA errors that lead to repeat expansion diseases

Rss Feed - Fri, 04/16/2021 - 11:01
Detecting hidden genetic defects by applying an existing method to an existing datasets. Researchers at Radboud university medical center have succeeded.

Shorter variations of high intensity interval training also improve health

Rss Feed - Fri, 04/16/2021 - 10:58
High intensity interval training has become increasingly popular as it's a quick and effective way to improve health.

Breast cancer treatment can be safely reduced in women over the age of 70

Rss Feed - Fri, 04/16/2021 - 10:53
Oncologists faced with treating older women with breast cancer often must decide if the treatment may be more detrimental than the cancer.

Survival data for immunotherapies should be re-analyzed for potential misinterpretation, indicates study

Rss Feed - Fri, 04/16/2021 - 10:46
Immune checkpoint inhibitors have transformed cancer care to the point where the popular Cox proportional-hazards model provides misleading estimates of the treatment effect, according to a new study published April 15 in JAMA Oncology.

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