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Researchers measure brain volume differences in HIV-infected individuals
Nearly 38 million people around the world are living with HIV, which, with access to treatment, has become a lifelong chronic condition. Understanding how infection changes the brain, especially in the context of aging, is increasingly important for improving both treatment and quality of life.
New review highlights heat-health outcome relationship in the urban context
Over the last half-century, the probability of heat extreme events has changed by orders of magnitude in almost every region of the world, with occurrences that are now up to a hundred times more in respect to a century ago.
Study: NTRK fusions are far more frequently seen in pediatric tumors
In a large study of pediatric cancer patients, researchers from Children's Hospital of Philadelphia have analyzed the frequency, fusion partners, and clinical outcome of neurotrophic tyrosine receptor kinase (NTRK) fusions, which are clinical biomarkers that identify patients suitable for treatment with FDA-approved TRK inhibitors.
National consortium to study the effects of emerging SARS-CoV-2 mutations
A new national research project to study the effects of emerging mutations in SARS-CoV-2 will be launched with £2.5 million of funding from UK Research and Innovation.
New review supports stricter control of HbA1C levels among children with type 1 diabetes
Diabetes is characterized by elevated levels of sugar or glucose (hyperglycemia) in the blood. This occurs due to the lack of the hormone insulin in type 1 diabetes, and to reduced insulin levels in combination with insulin resistance in type 2 diabetes.
Study reveals significant role of ADAMTS1 protein in uveal melanoma
Scientists from the University of Granada and GENYO (Pfizer-University of Granada-Andalusian Government Centre for Genomics and Oncological Research), in a study led by Juan Carlos Rodríguez-Manzaneque, have demonstrated the significant role of a protein called ADAMTS1 in uveal melanoma, one of the rarest and most aggressive cancers that exist, which develops in the eye.
Patients with schizophrenia have increased risk of Parkinson's disease, shows study
A new study conducted at the University of Turku, Finland, shows that patients with a schizophrenia spectrum disorder have an increased risk of Parkinson's disease later in life.
Severe COVID-19 linked to genetic make-up of both host and virus, say researchers
A recent study conducted by a team of international scientists has revealed that the infectivity and pathogenicity of SARS-CoV-2 strongly depend on the genetic background of both the virus and the host.
White-tailed deer susceptible to SARS-CoV-2 infection, study finds
A team of scientists recently demonstrated that white-tailed deer are highly susceptible to SARS-CoV-2 infection. Moreover, the infected animals are capable of transmitting the virus to their non-infected counterparts via indirect contact.
Image-based deep learning haplotype-guided study maps the global adaptation of SARS-CoV-2
A new study used deep learning with image recognition technology to trace the emergence of variants with increased viral fitness. Higher fitness leads to rapid expansion of these lineages in the areas where they are introduced. This type of study could facilitate the development of more effective antibodies and vaccines to help contain the pandemic.
What are the SARS-CoV-2 exposure risks for workers on mink farms?
A new study reports on the risk of COVID-19 among workers on these farms, and in the communities living around such farms.
Can cloth masks protect healthcare professionals from SARS-CoV-2?
Given the global scarcity of surgical masks, a recent review study examines this issue - dealing with the potential use of cloth masks in healthcare scenarios.
Study reports promising new monoclonal antibody against SARS-CoV-2’s spike protein
An encouraging new study describes a promising new therapeutic antibody that shows potent neutralizing activity against SARS-CoV-2, the causative agent of COVID-19.
Study to examine if changing mealtimes could reduce the risk of Type 2 diabetes
An innovative new study is set to examine if changing our mealtimes to earlier or later in the day could reduce the risk of developing Type 2 diabetes.
Study shows why antihistamine drugs fail to control severe itch in eczema patients
In addition to a skin rash, many eczema sufferers also experience chronic itching, but sometimes that itching can become torturous. Worse, antihistamines -- the standard treatment for itching and allergy -- often don't help.
New DNA test quickly identifies secondary infections in COVID-19 patients
Researchers have developed a DNA test to quickly identify secondary infections in COVID-19 patients, who have double the risk of developing pneumonia while on ventilation than non-COVID-19 patients.
Researchers to study potential treatment for limb dysfunction in patients with chronic spinal cord injury
Ghaith Androwis, PhD, and Steven Kirshblum, MD, received a grant from BrainQ Technologies to study a potential treatment for arm and hand dysfunction in individuals with chronic spinal cord injury.
New drug reduces tumor volume and pain in patients with neurofibromatosis type 1
Based on preclinical studies of an investigational drug to treat peripheral nerve tumors, researchers at Children's Hospital of Philadelphia (CHOP) as part of the Neurofibromatosis Clinical Trials Consortium have shown that the drug, cabozantinib, reduces tumor volume and pain in patients with the genetic disorder neurofibromatosis type 1 (NF1).
Researchers use deep learning to study the effect of mental illness and other disorders on the brain
Compared to standard machine learning models, deep learning models are largely superior at discerning patterns and discriminative features in brain imaging, despite being more complex in their architecture, according to a new study in Nature Communications led by Georgia State University.
Meniscal and mechanical symptoms do not predict findings on knee arthroscopy
Orthopaedic surgeons have traditionally been taught that certain types of knee symptoms indicate damage to specialized structures called the menisci.