Comparing the Morphological Changes in Burn Wound Tissues and the Procalcitonin Concentration

Ludmila I. Budkevich, PhD, ScD², Andershan U. Lecmanov PhD, ScD¹,², Elena G. Kolokolchikova, PhD, ScD³, Vera V. Soshkina, PhD¹

¹Moscow Scientific Research Institute of Pediatrics & Pediatric Surgery, Moscow, Russian Federation.²Moscow Children’s Hospital #9, Moscow, Russian Federation,   ³N. V. Sclifosovsky Research Institute of Emergency Care, Moscow, Russian Federation

*Corresponding author: Vera V. Soshkina, PhD, Moscow Scientific Research Institute of Pediatrics & Pediatric Surgery. Moscow, Russian Federation.  E-mail:

Published: March 25, 2013


The problem of early diagnostics of bacterial complications is particularly true for children with extensive burn trauma (BT). Procalcitonin concentration levels considerably facilitate the diagnosis of sepsis. In all, 50 children with severe burns were included in our research. We conducted histological tests of the burn wound tissues from 13 patients. On comparison of the results of the PCT-tests with the results of the morphological investigation, we observed that the depth of the penetration of the microorganisms in the damaged tissues quite precisely corresponded to changes in the procalcitonin concentration.

burn trauma; PCT-tests; procalcitonin.
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