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The effects of tirzepatide on adults with obesity and moderate-to-severe obstructive sleep apnea.

Treating a wound or an inflammation directly where it occurs has clear advantages: The active ingredient reaches its target immediately, and there are no negative side effects on uninvolved parts of the body.

We get healthy dietary fibres from consuming fruits, vegetables, and whole grains. But why are the fibres so good for us? A team of researchers has discovered that dietary fibres play a crucial role in determining the balance between the production of healthy and harmful substances by influencing the behavior of bacteria in the colon.

Researchers will investigate the relationship between breastfeeding and breast cancer, thanks to new funding from Breast Cancer Now.

Young people aged 14 to 20 years are nowadays more satisfied with being single than their counterparts ten years ago. This is the conclusion of a study undertaken by the Institute of Psychology at Johannes Gutenberg University Mainz (JGU).

Research in nonhuman primates is opening the possibility of testing treatments for the early stages of Alzheimer’s and similar diseases, before extensive brain cell death and dementia set in.

Brigham, Broad and Harvard Chan School researchers found that specific species and strains of bacteria were linked to changes in the functioning of the gut microbiome and a person's risk of type 2 diabetes.

Type-2 helper T (Th2) cells play intricate roles in the inflammatory response underlying asthma. Elevated levels of the protein GATA3 stimulate the maturation of these cells. Consequently, gene regions known as enhancers, which enhance the expression of the GATA3 gene, have been implicated in asthma-associated inflammation.

Diabetes significantly increases the risk of cancer, particularly in people aged 40-54 years, new research shows.

Children who report being more empathetic are more likely to show signs of poorer health in the face of more interparental conflict than less empathetic children, according to a new study led by researchers in the Penn State College of Health and Human Development.

A new study by Penn researchers examined, for the first time, the differences in lung transplant graft outcomes from organs recovered from the two types of deceased organ donor care facilities operating in the United States. The research, published today in JAMA Network Open, offers insights that could improve the organ donation and transplantation process for patients across the nation.

Studies of mouse models of Fragile X syndrome and Phelan-McDermid syndrome show that treatment with cannabidiol (CBD) and the diabetes drug metformin can alleviate behavioral difficulties, according to research presented today (Wednesday) at the Federation of European Neuroscience Societies (FENS) Forum 2024.

People are not very good at distinguishing between human voices and voices generated by artificial intelligence (AI), but our brains do respond differently to human and AI voices, according to research presented today (Tuesday) at the Federation of European Neuroscience Societies (FENS) Forum 2024.

The SELECT trial found that semaglutide significantly reduces cardiovascular events in individuals with overweight or obesity and preexisting cardiovascular disease, regardless of baseline HbA1c or changes in HbA1c levels.

The BEDROC trial found that extended-release ketamine tablets (R-107) significantly improve depressive symptoms in treatment-resistant depression patients, with the 180 mg dose showing the most efficacy. The treatment was well-tolerated with minimal side effects.

The FLOW trial demonstrated that semaglutide significantly improves kidney and cardiovascular outcomes in people with chronic kidney disease and type 2 diabetes, irrespective of SGLT2 inhibitor use.

AI tools are revolutionizing cardiovascular healthcare by enhancing diagnostics, prognostics, and biomarker detection, thus improving the precision and efficacy of care. The review also addresses the potential risks and challenges in integrating AI into clinical workflows.

In a significant finding, researchers from The Jackson Laboratory (JAX) and UConn Health have discovered that sodium valerate, a short-chain fatty acid produced by gut microbes, can dramatically reduce binge drinking behavior and blood ethanol concentration in mice.

In a first-of-its-kind study, researchers compared the efficacy of preventative therapy for spinal muscular atrophy (SMA) between two well-matched study groups, using either gene therapy (onasemnogene abeparvovec) alone or in combination with risdiplam (oral medication) or nusinersen (intrathecal injection) administered before apparent signs of disease emerged.

Researchers from the University of Michigan Health Rogel Cancer Center have discovered a biomarker that could help identify which renal cancer patients have a higher risk of recurrence.