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Step steady: Consistent walking improves brain function in older adults

Rss Feed - Mon, 04/08/2024 - 23:25
Study highlights that stabilizing daily step variability, rather than increasing total step counts, improves cognitive flexibility in older adults following a 10-week physical activity intervention.

Gut microbiome shows no clear link to cognitive impairments in Parkinson's disease

Rss Feed - Mon, 04/08/2024 - 23:07
Study investigates the gut microbiome's role in Parkinson's disease patients with mild cognitive impairments, revealing no distinct microbiome signatures associated with MCI in PD compared to cognitively normal PD patients or controls.

Beta-blockers show no benefit for heart attack patients with normal heart function

Rss Feed - Mon, 04/08/2024 - 22:53
The REDUCE-AMI trial found that long-term beta-blocker therapy does not reduce mortality risk in acute myocardial infarction patients with preserved left ventricular ejection fraction compared to no beta-blocker treatment.

Adherence to the EAT-Lancet diet reduces the risk of heart failure

Rss Feed - Mon, 04/08/2024 - 22:37
Adherence to the EAT-Lancet diet, rich in plant-based foods, is associated with a reduced risk of heart failure, potentially mediated by specific plasma proteins, in a large population-based cohort study.

Nirmatrelvir fails to shorten COVID-19 symptoms in latest trial

Rss Feed - Mon, 04/08/2024 - 22:03
A study in The New England Journal of Medicine evaluates the combination of nirmatrelvir and ritonavir against COVID-19, finding it does not significantly reduce symptom duration in vaccinated or unvaccinated adult outpatients.

Denmark's pertussis epidemic reveals the power of maternal vaccination

Rss Feed - Mon, 04/08/2024 - 21:56
A study published in Eurosurveillance details the 2023 pertussis epidemic in Denmark, emphasizing the age-specific incidence, the role of maternal vaccination in reducing infant hospitalizations, and the impact of vaccination strategies on managing the outbreak.

Study shows association between low youth cardiorespiratory fitness and adulthood decreased work ability

Rss Feed - Mon, 04/08/2024 - 16:45
A study from the University of Jyväskylä confirms the concerns raised in the public domain about how young people's decreased fitness may affect their future work ability.

Remote monitoring for COVID-19 patients shows no benefit from pulse oximetry

Rss Feed - Mon, 04/08/2024 - 16:31
Using a pulse oximeter to measure oxygen levels is no better than just regularly asking patients with COVID-19 if they are short of breath, according to new research at the Perelman School of Medicine of the University of Pennsylvania.

SMART trial shows comparable outcomes of two common TAVR devices in small aortic annulus patients

Rss Feed - Mon, 04/08/2024 - 16:03
People with a small aortic annulus, a part of the heart's anatomy where the left ventricle meets the aorta, who underwent transcatheter aortic valve replacement (TAVR) with a supra-annular self-expanding valve saw similar clinical outcomes and superior valve performance at one year compared with those who underwent TAVR with a balloon-expandable valve, according to research presented at the American College of Cardiology's Annual Scientific Session.

Edetate disodium-based chelation ineffective for heart attack patients with diabetes

Rss Feed - Mon, 04/08/2024 - 15:59
People with diabetes who had suffered a heart attack derived no clinical benefit from edetate disodium-based chelation, a therapy that draws lead and other toxic metals linked to increased risk of heart disease and stroke out of the body, according to a study presented at the American College of Cardiology's Annual Scientific Session.

Study shows reduced bleeding risk with ticagrelor monotherapy after percutaneous coronary intervention

Rss Feed - Mon, 04/08/2024 - 15:56
People who have had a heart attack or who are at risk for a heart attack and who stopped taking aspirin alongside the P2Y12 inhibitor ticagrelor one month after undergoing percutaneous coronary intervention (PCI) saw a significantly reduced risk of clinically meaningful bleeding with no increased risk of clotting-related adverse events at 12 months compared with patients who continued taking aspirin and ticagrelor for a full year, in a study presented at the American College of Cardiology's Annual Scientific Session.

Lerodalcibep reduces LDL cholesterol by over 50% in high-risk patients

Rss Feed - Mon, 04/08/2024 - 13:40
Among patients at high or very high risk for a heart attack or stroke, the addition of the investigational drug lerodalcibep to standard cholesterol-lowering medication for one year reduced LDL, or "bad" cholesterol, levels by more than half on average, compared with a placebo.

Impella CP pump shows survival benefit in cardiogenic shock

Rss Feed - Mon, 04/08/2024 - 13:36
Implantation of the Impella CP micro-axial flow pump in the hours after a heart attack significantly increased the rate of survival at six months among people suffering cardiogenic shock, according to a study presented at the American College of Cardiology's Annual Scientific Session.

Novel cholesterol removal strategy shows potential benefits post-heart attack

Rss Feed - Mon, 04/08/2024 - 13:28
The first trial of a novel strategy for removing cholesterol from patients' arteries did not reduce the risk of death, heart attack or stroke within three months of a prior heart attack, according to research presented at the American College of Cardiology's Annual Scientific Session. However, the findings suggest that the strategy may be beneficial with longer follow-up.

Study: Empagliflozin shows mixed results in heart attack patients

Rss Feed - Mon, 04/08/2024 - 13:21
Use of the sodium glucose cotransporter-2 (SGLT-2) inhibitor empagliflozin following a heart attack did not show a significant benefit in reducing overall heart failure hospitalizations or death from any cause, according to a study presented at the American College of Cardiology's Annual Scientific Session.

Study provides insights on lung transplantation in advanced age candidates

Rss Feed - Mon, 04/08/2024 - 13:15
Data from the International Society for Heart and Lung Transplantation (ISHLT) indicates that the proportion of recipients aged 66 and above has risen to 19% by 2017.

Interatrial shunt may offer differential benefits based on heart failure type

Rss Feed - Mon, 04/08/2024 - 13:02
Patients with heart failure who had a small shunt inserted between the heart's left and right atria did not see any significant benefits overall compared with those who received a placebo procedure after a median of 22 months follow-up, in a study presented at the American College of Cardiology's Annual Scientific Session.

MADs show comparable blood pressure reduction to CPAP in hypertensive patients with sleep apnea

Rss Feed - Mon, 04/08/2024 - 12:57
People with hypertension and obstructive sleep apnea were no less likely to see their blood pressure drop over six months if they used a mandibular advancement device (MAD), which is inserted onto the teeth similar to a bite guard.

App-based therapy offers significant improvement for men with bladder emptying disorders

Rss Feed - Mon, 04/08/2024 - 12:51
Combining pelvic floor exercises with behavioral therapy could be more effective than current medical treatments at helping men with frequent urges to urinate, new research in men has found.

Healthy eating, physical activity, and medication: Type 2 diabetes patients' willingness to engage varies

Rss Feed - Mon, 04/08/2024 - 11:08
The willingness to engage in various management options for T2D among recently diagnosed patients.

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