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A promising therapy that treats blood cancers by harnessing the power of the immune system to target and destroy cancer cells could now treat solid tumors more efficiently. Thanks to a recent study published in Molecular Therapy – Methods & Clinical Development from Dan Cappabianca and Krishanu Saha at the Wisconsin Institute for Discovery, Chimeric Antigen Receptor (CAR) T-cell therapy can be improved by altering the conditions the T cells are grown in. And it was all discovered by chance.

A new groundbreaking study sheds light on a medical question scientists have long wondered: why do 40 per cent of children with the rare neurodevelopmental disorder KBG syndrome have heart defects? The research now points to a critical link between the heart and the brain.

While investigating two boys from different families with severe obesity, anxiety, autism, and behavioural problems triggered by sounds or smells, a team led by scientists at the University of Cambridge, UK, and Baylor College of Medicine, Houston, USA, discovered that the boys were missing a single gene, known as TRPC5, which sits on the X chromosome.

A multinational team led by Weill Cornell Medicine investigators developed a test that will help measure the persistence of HIV in people affected by viral strains found predominantly in Africa-;a vital tool in the search for an HIV cure that will benefit patients around the world.

Liver diseases are commonly diagnosed using serum enzyme assays, particularly for aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyl transpeptidase (GGT), and 5'-nucleotidase (5'-NT).

Transgender, nonbinary, and gender-diverse people face barriers to accessing surgery and to the health system in general, describe authors in two new research papers published in CMAJ (Canadian Medical Association Journal).

Study reveals a significant rise in ADHD diagnoses and medication use in Finland during the COVID-19 pandemic, highlighting the pandemic's impact on mental health recognition, especially among young women and older adults.

Study demonstrates that six months of high-impact unilateral exercise significantly improves femoral neck bone density in postmenopausal women without negatively affecting knee osteoarthritis progression.

Neuroendocrine tumors, including small cell lung cancer and neuroendocrine prostate cancer, are very aggressive with high chances of spreading.

A world-first study has found low-dose aspirin may treat flu-induced blood vessel inflammation, creating better blood flow to the placenta during pregnancy.

Using artificial intelligence, Garvan Institute researchers have found potential cancer drivers hidden in so-called 'junk' regions of DNA, opening up possibilities for a new approach to diagnosis and treatment.

We set out to identify genes that are commonly expressed in CD8+ T cells, killer immune cells that can drive anti-tumor immunity, across many types of human cancers.

Already at the beginning of the COVID-19 pandemic, a group of Brazilian researchers pioneered in showing why SARS-CoV-2 infection tends to be more severe in diabetic patients.

Study explores the evolutionary significance of baby schema, highlighting how infant features trigger caregiving behaviors in humans and other animals.

A major challenge in developing a vaccine for HIV is that the virus mutates fast-;very fast. Although a person initially becomes infected with one or a few HIV strains, the virus replicates and mutates quickly, resulting in a "swarm" of viral strains existing in a single body.

Dynamic interactions with viruses and bacterial pathobionts significantly enhance nasal innate immunity in children, revealing distinct immunophenotypes driven by microbial load and type.

The incidence of low birth weight rose sharply in India amid the COVID-19 pandemic, according to new research from the University of Notre Dame.

A common infection-causing bacteria was much less likely to evolve antibiotic resistance when treated with a mixture of antimicrobial peptides rather than a single peptide, making these mixtures a viable strategy for developing new antibiotic treatments.

The Mediterranean Diet is a powerful ally for health even after a cancer diagnosis. This is the key result of an Italian study carried out as part of the UMBERTO Project, conducted by the Joint Research Platform Umberto Veronesi Foundation - Department of Epidemiology and Prevention of the I.R.C.C.S. Neuromed of Pozzilli, in collaboration with the LUM "Giuseppe Degennaro" University of Casamassima (BA).

Randomized controlled trials, or RCTs, are believed to be the best way to study the safety and efficacy of new treatments in clinical research.