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Targeting basophils to revitalize cytotoxic T-cells in tumor microenvironment
The ecosystem that surrounds a tumor, also known as the tumor microenvironment, includes immune cells, tissues, blood vessels and other cells that interact with each other and with the tumor.
Study: Out-of-pocket costs impact naloxone access
Patients are less likely to fill prescriptions for naloxone when they face increases in out-of-pocket costs, according to research by the University of Michigan.
Study sheds light on pediatric DIPG tumor mechanisms
Researchers at the University of Michigan Health Rogel Cancer Center are one step closer to understanding how pediatric DIPG tumors work.
Study advocates for liberal blood transfusions in TBI intensive care
Increased use of blood transfusions after major traumatic brain injury could help people hospitalized in intensive care units regain greater functional independence and a better quality of life.
Study highlights benefits of ADHD medications for pregnant patients with opioid use disorder
Opioid overdoses for pregnant patients are at an all-time high in the United States, even as overall numbers are improving.
New psychotherapy shows promise in reducing chronic pain for older veterans
A new study led by UCLA Health and the U.S. Veterans Affairs Office found chronic pain among older adults could be significantly reduced through a newly developed psychotherapy that works by confronting past trauma and stress-related emotions that can exacerbate pain symptoms.
Physical activity and cognitive training can improve mood for adults with Down's syndrome
A new study has discovered that physical activity and cognitive training can improve levels of life satisfaction and mood for adults with Down's syndrome.
Dose reduction of glucocorticoids in systemic lupus erythematosus
Glucocorticoids are a mainstay of treatment for systemic lupus erythematosus (SLE). But due to long-term adverse effects, dose reduction is becoming a crucial part of treat-to-target management goals.
New insights into blood precursors of pathogenic macrophages in RA
The exact origin and precursor differentiation route of tissue macrophages remains controversial. At the 2024 congress of EULAR - The European Alliance of Associations for Rheumatology - new work sheds light on blood precursors of pathogenic tissue macrophages.
Study demonstrates efficacy of treat-to-target in early axial spondyloarthritis
Early therapeutic interventions in inflammatory rheumatic diseases have proven successful in inducing drug-free remission, and EULAR - The European Alliance of Associations for Rheumatology - recommends early intervention in arthritis, since conventional synthetic disease-modifying antirheumatic drugs (csDMARD) have been shown to slow disease progression in both rheumatoid and psoriatic arthritis.
Study shows increase in mandatory flu vaccinations for hospital staff
In just a few months, hospitals and health systems nationwide will start working to vaccinate as many staff as possible against the flu.
Approximately 1 in 6 patients experience antidepressant withdrawal symptoms, systematic review finds
Researchers performed a meta-analysis to determine the prevalence of antidepressant discontinuation symptoms.
Large-scale study presents findings on implications of plant vs animal ultra-processed foods on cardiovascular disease risk
In the present study, researchers investigated cardiovascular disease risk among British individuals based on their dietary intake of food groups of plant or animal origin and food processing categories.
Study uncovers why targeted therapy fails in some non-small cell lung cancer patients
The reason why targeted treatment for non-small cell lung cancer fails to work for some patients, particularly those who have never smoked, has been discovered by researchers from UCL, the Francis Crick Institute and AstraZeneca.
Access to urban vegetation can mitigate asthma risk for children, study finds
How urban vegetation and exposure to pollen are linked to the incidence of childhood asthma.
Study links antidepressant use and epigenetic aging to higher mortality risk in postmenopausal women
The impact of depressive symptoms, use of antidepressants, and epigenetic age acceleration (EAA) on mortality in postmenopausal individuals.
Replacing TV time with light activity or sleep boosts healthy aging odds
Sedentary behavior reduces the odds of healthy aging, while light physical activity increases them. Replacing TV time with light activity, exercise, or sleep improves healthy aging odds.
Study confirms no causal link between COVID-19 and ischemic priapism
A study in the International Journal of Impotence Research found no causal link between COVID-19 and ischemic priapism, with priapism occurring across all COVID-19 severity levels and treatments remaining effective.
Combining donepezil and memantine extends lives of Alzheimer's patients, study finds
Alzheimer's disease is the world's most common neurodegenerative disease, affecting more than 50 million people globally.
New research sheds light on IL-23's role in chronic inflammatory bowel diseases
Scientists at Weill Cornell Medicine discovered a previously unknown link between two key pathways that regulate the immune system in mammals-;a finding that impacts our understanding of chronic inflammatory bowel diseases (IBD).