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Breakthrough in enzyme communication could pave the way for new drugs
A mechanism that could help scientists harness enzymes for use in drug discovery has been discovered in a research breakthrough at the University of Birmingham.
Simple test could revolutionize diagnosis of life-threatening genetic arrhythmia
A team of international researchers has revealed a new, simple clinical test to detect Calcium Release Deficiency Syndrome (CRDS), a life-threatening genetic arrhythmia that causes dangerously fast heartbeats and can lead to severe complications such as sudden cardiac arrest and death.
Role of SMIM1 gene in obesity uncovered
Scientists have discovered a new cause of why people who lack a specific blood group are genetically predisposed to be overweight or obese.
Modified form of chemotherapy before and after surgery enhances survival in pancreatic cancer patients
Patients with pancreatic cancer who received chemotherapy both before and after surgery experienced longer survival rates than would be expected from surgery followed by chemotherapy, according to a new study from researchers at Yale Cancer Center (YCC) and Yale School of Medicine.
Challenges in treatment of cholangiocarcinoma in patients with primary sclerosing cholangitis
Primary sclerosing cholangitis (PSC) is a rare progressive liver disease that damages bile ducts and significantly increases the risk of bile duct cancer, particularly a type called cholangiocarcinoma (CCA).
Unveiling the role of SOS genes in E. coli survival during antibiotic treatment
When E. coli detects damage to its genetic material, it sends out an SOS signal that alters activity inside the cells.
Premenopausal oophorectomy reduces white matter integrity in the brain later in life
Women who have their ovaries removed before menopause, particularly before the age of 40, have reduced white matter integrity in multiple regions of the brain later in life.
How attractive appearance leads to more risky behavior among young people
New research challenges the notion that good looks are the key to happiness. It turns out that an attractive appearance leads to more risky behavior among young people.
Study reveals genetic associations between coffee and harmful health outcomes such as obesity and substance use
Scientists have found consistent positive genetic correlations of coffee intake with substance use and obesity in US and UK adults of European ancestry.
One copy of the Christchurch variant may confer protection against familial Alzheimer's disease
A scientific story that began with a discovery in just one extraordinary patient is now panning out. In 2019, an international team that included researchers from two Mass General Brigham hospitals -; Mass Eye and Ear and Massachusetts General Hospital (MGH)-; reported on the case of a patient who did not develop cognitive impairment until her late 70s, despite being part of a family at extremely high genetic risk for developing early-onset Alzheimer's disease.
Study finds increase in cannabis-related disorders among pregnant women post legalization
In October 2018, Canada enacted the Cannabis Act in Canada (CAC), which legalised the non-medical use of cannabis.
Walking reduces recurrence of low back pain, study finds
Adults with a history of low back pain went nearly twice as long without a recurrence of their back pain if they walked regularly, a world-first study has found.
Less healthy intestinal flora could increase the risk of serious infection
The composition of the intestinal flora can predict the chances of developing serious infections such as pneumonia.
Exercising at night improves glucose control in overweight adults
Researchers explore differences in the timing physical activity and its impact on blood glucose levels and metabolic function.
High-fat diet triggers anxiety in male rats through gut-brain axis disruption
Researchers investigate the impact of a high-fat diet on gut microbiome diversity and its effects on anxiety-related symptoms.
Proteins in blood may help to predict Parkinson’s disease up to seven years before the onset of motor symptoms
Researchers combined mass spectrometry-based proteomic phenotyping with machine learning to identify blood biomarkers in early Parkinson's disease.
Several key policies to stop the spread of COVID-19 were generally a good idea in hindsight according to majority of Americans
The Harvard T.H. Chan School of Public Health and the de Beaumont Foundation present findings from a national poll they conducted to obtain public views on COVID-19 pandemic-related policies.
Young adults with periodontitis at higher risk for cryptogenic ischemic stroke
Periodontitis, a common condition, has been linked to a specific type of ischemic stroke.
Yeast-fermented bread shows promise in preventing asthma symptoms
The effects of a functional bread fermented with yeast (Saccharomyces cerevisiae) in asthma prevention.
Study reveals cognitive benefits of ketogenic diet in aged mice
The impact of cyclic ketogenic diet treatments in improving the age-related decline in brain function.