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PFDN6 protein could be a new target for colorectal cancer treatment

Rss Feed - Thu, 06/27/2024 - 23:20
Researchers have identified a protein called PFDN6 that may play a role in the development and spread of colorectal cancer (CRC).

Study uncovers role of Y chromosome loss in transthyretin cardiac amyloidosis

Rss Feed - Thu, 06/27/2024 - 23:15
Researchers at Boston Medical Center (BMC) and Boston University (BU) Chobanian & Avedisian School of Medicine, in collaboration with an international team of scientists, shared findings from a new study published in the American Heart Association journal, Circulation: Heart Failure that explores a common cause of heart disease in older men called transthyretin cardiac amyloidosis (ATTR-CA).

Study exposes algorithmic inequity in endometrial cancer detection for Black women

Rss Feed - Thu, 06/27/2024 - 23:08
A common algorithm to check for endometrial cancer is not reliable for Black women, according to a new study published today in JAMA Oncology.

Dietary fiber intake reshapes tryptophan metabolism, promoting gut health and reducing disease risks

Rss Feed - Thu, 06/27/2024 - 21:00
A recent study in Nature Microbiology reveals that increased dietary fiber intake directs microbial tryptophan metabolism, leading to health benefits such as improved gut mucosa integrity and reduced risk of metabolic disorders.

Understanding the role of vaccination in mitigating long COVID brain fog

Rss Feed - Thu, 06/27/2024 - 14:08
Since the outset of the COVID-19 pandemic, 10 to 30 per cent of the general population has experienced some form of virus-induced cognitive impairment, including trouble concentrating, brain fog or memory loss.

Study reveals the adverse effects of prenatal exposure to ethylene oxide on fetal development

Rss Feed - Thu, 06/27/2024 - 13:59
A study led by the Barcelona Institute for Global Health (ISGlobal), a centre supported by the "la Caixa" Foundation, provides new evidence on the adverse effects of prenatal exposure to ethylene oxide (EO) on foetal development.

Enhancing neighborhood opportunities can be a promising approach to promote infant development

Rss Feed - Thu, 06/27/2024 - 13:52
Growing up in neighborhoods with more educational and socioeconomic opportunities has a positive impact on infants' brain activity, according to new research from Boston Medical Center (BMC).

Elementary age children more likely to experience non-sports and recreation-related concussions

Rss Feed - Thu, 06/27/2024 - 13:39
Researchers from Children's Hospital of Philadelphia (CHOP) found that young children between the ages of 5 and 12 were more likely to experience a concussion from recreation and other non-sport activities, yet those injuries were not seen by specialists until days later compared with sports-related concussions in the same age group.

Exposure to urban green and blue spaces may lower odds of having coronary artery calcification

Rss Feed - Thu, 06/27/2024 - 13:31
Being near and having more exposure to urban green space and blue (water) space is linked to lower odds of having coronary artery calcification in middle age, which is an early marker of cardiovascular disease.

Targeted gene therapy may reduce AML burden and protect the heart from cardiotoxicity

Rss Feed - Thu, 06/27/2024 - 13:12
Researchers from the University of Missouri School of Medicine found that a targeted gene therapy may make acute myeloid leukemia (AML) more sensitive to chemotherapy, while also protecting the heart against toxicity often caused by cancer treatments.

Precise intensity-modulated radiotherapy outperforms 3D-CRT in advanced lung cancer

Rss Feed - Thu, 06/27/2024 - 12:59
Results from a new study led by researchers at The University of Texas MD Anderson Cancer Center support standard use of the more precise intensity-modulated radiotherapy (IMRT) over the alternative 3D-conformal radiotherapy (3D-CRT) for patients with unresectable, locally advanced non-small cell lung cancer (NSCLC).

Study identifies mechanism that impedes the effectiveness of melanoma therapies

Rss Feed - Thu, 06/27/2024 - 12:46
In many cases of malignant melanoma, the effect of targeted treatment is lost over time. A research team from UZH and USZ has now discovered that a factor secreted by tumor cells is responsible for the resistance.

Study reveals mental health challenges among LGBTQ+ farmers in the U.S.

Rss Feed - Thu, 06/27/2024 - 12:22
LGBTQ+ people involved in U.S. farm work are over three times more likely to experience depression and suicidal intent and about two and a half times more likely to experience anxiety than the general population.

Assessing clinical benefit and safety in trial waivers for treatment-refractory cancers

Rss Feed - Thu, 06/27/2024 - 12:06
Patients with treatment-refractory cancers who received eligibility and testing waivers to participate in a large basket/umbrella oncology trial had similar rates of clinical benefit and adverse events as patients who participated in the trial without waivers.

Discovery of nanoparticle-based drug delivery system could revolutionize schizophrenia treatment

Rss Feed - Thu, 06/27/2024 - 10:17
Schizophrenia is a complicated mental health disorder accompanied by wide range of symptoms such as hallucinations, impaired cognitive ability, and disorganized speech or behavior.

Uptick in early-onset gastrointestinal cancers raises the need for better prevention and diagnosis

Rss Feed - Thu, 06/27/2024 - 10:09
Treatment of gastrointestinal (GI) cancers is catching up with other areas of oncology and offering patients better prospects for survival and quality of life, but a significant uptick in early-onset cases is raising new questions about effective prevention, diagnosis and treatment.

Fighting cancer with nanoparticles

Rss Feed - Thu, 06/27/2024 - 06:10
Nanoparticles may be the future of the fight against pancreatic cancer, but also tumours that currently have no cure options. A video news release provides a synthesis of the ULISES project milestones.

Chronic loneliness associated with higher stroke risk independent of depressive symptoms or social isolation

Rss Feed - Thu, 06/27/2024 - 05:02
Researchers determined the relationship between loneliness and incident stroke risk in the United States.

AI breakthrough: Speech analysis predicts Alzheimer's progression with 78.5% accuracy

Rss Feed - Thu, 06/27/2024 - 04:48
A method for predicting Alzheimer’s disease (AD) progression.

Diabetes decoded: How your gut microbiome influences disease risk

Rss Feed - Thu, 06/27/2024 - 04:10
How microbial features and functions specific to subspecies and strains contribute to the pathological mechanisms of type 2 diabetes.

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