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Latest Medical Research News and Research
Updated: 20 min 51 sec ago

Antiviral strategy using synthetic peptoid has promising implications for fighting infection

Tue, 08/24/2021 - 15:30
Scientists have manufactured a synthetic form of peptide to combat viral infections, with tests already conducted on HSV-1 as well as SARS-CoV-2.

Newly developed CPAP System provides a cost-effective respiratory device for COVID patients

Tue, 08/24/2021 - 15:06
In an attempt to make breathing devices available to low-income areas, scientists have developed the LeVe CPAP System for respiratory support to treat COVID.

Maintaining good hydration throughout life may reduce the risk of heart failure

Tue, 08/24/2021 - 11:46
Staying well hydrated throughout life could reduce the risk of developing heart failure, according to research presented at ESC Congress 2021.

Family history is not the only predisposing factor for premature heart attacks, study suggests

Tue, 08/24/2021 - 11:42
Young heart attack victims are more likely to be smokers, obese, and have high blood pressure or diabetes compared to their peers, according to research presented at ESC Congress 2021.

SARS-CoV-2 Delta variant associated with more breakthrough infections

Tue, 08/24/2021 - 10:48
The study highlights that compared to the previously circulating alpha variant, the delta variant is associated with higher infectious virus load and a lower level of humoral immunity in the upper respiratory tract. The study is currently available on the medRxiv* preprint server prior to peer review.

UCR researchers gauge social responsibility in reducing COVID-19 spread

Tue, 08/24/2021 - 10:18
Uncertainty and anxiety generated by the COVID-19 pandemic motivated social psychologist Evelyn Vázquez at the University of California, Riverside, to collaborate with UCR Healthy Campus on a study to identify safety measures and public health messaging that reduce the spread of the coronavirus within campus communities.

Frameshift deletion mutation in ORF7a may provide fitness advantage to Australia's SARS-CoV-2 delta variants

Tue, 08/24/2021 - 10:09
A team of scientists from Australia has recently identified a frameshift deletion mutation in ORF7a of the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The mutation results in the production of a truncated peptide with altered functionality. The study is currently available on the medRxiv* preprint server while awaiting peer review.

Study shows higher risk of sarcopenia among older adults who are underweight and lack exercise

Tue, 08/24/2021 - 09:58
Analysis of medical data from around 1800 65-year-old residents of Kobe, a large Japanese city, has shown that at least 3% have possible sarcopenia (*1), revealing that the risks are higher in those who are underweight and don't exercise enough.

Study suggests a novel therapeutic target to reverse lung fibrosis

Tue, 08/24/2021 - 09:45
Researchers have reversed lung fibrosis in a mouse model of idiopathic pulmonary fibrosis, or IPF, as reported in a study published in the journal Cell Death and Differentiation.

Patients on dialysis show reduced antibody levels four months after COVID-19 vaccination

Tue, 08/24/2021 - 09:41
A new longitudinal study posted to the medRxiv* preprint server suggests vaccinated patients on chronic hemodialysis having waning immunity against severe acute respiratory syndrome 2 (SARS-CoV-2) variants of concern. The German researchers found a drop in neutralizing antibody levels and T cell activity four months after receiving their second Pfizer-BioNTech vaccine.

Extreme novel pandemics more likely to occur in the future, statistical study reveals

Tue, 08/24/2021 - 09:40
The COVID-19 pandemic may be the deadliest viral outbreak the world has seen in more than a century. But statistically, such extreme events aren't as rare as we may think, asserts a new analysis of novel disease outbreaks over the past 400 years.

Synthetic SARS-CoV-2 vs. SARS-CoV-2

Tue, 08/24/2021 - 09:15
Though vaccination efforts are underway in most countries, there are still limited options for treating COVID-19. Now, researchers at Penn State designed a new COVID-19 therapy that uses a defective synthetic version of the SARS-CoV-2 virus to interfere with the actual virus's replication.

Study pinpoints an enzyme with a significant impact on SARS-CoV-2 replication

Tue, 08/24/2021 - 08:51
By applying a systems biology approach, a recent bioRxiv* preprint research paper by scientists from the Icahn School of Medicine at Mount Sinai in New York unveils interactions between the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) and p38 mitogen-activated protein kinase (MAPK) pathway responsible for regulating the expression of crucial inflammatory mediators in human lung epithelial cells.

Study suggests algorithm may help optimize future COVID-19 vaccine design

Tue, 08/24/2021 - 08:30
Scientists predict the COVID-19 pandemic is on its way to becoming endemic. The rising spread of COVID-19 variants such as Delta has helped infect unvaccinated and some vaccinated individuals. COVID-19 vaccines continue to be the best way to protect against severe illness and death, but there may be a need for vaccines to protect against a specific variant.

Researchers identify a brief window of opportunity to prevent NF1-associated optic pathway glioma

Tue, 08/24/2021 - 08:22
Researchers at Children's National Hospital identified a vulnerability in a developmental signaling pathway that can be hijacked to drive pediatric low-grade glioma (pLGG) formation, according to a pre-clinical study published in Developmental Cell.

Study identifies a novel potential biomarker for hepatocellular carcinoma

Tue, 08/24/2021 - 08:14
Aging-US published "Comprehensive analysis of the competing endogenous circRNA-lncRNA-miRNA-mRNA network and identification of a novel potential biomarker for hepatocellular carcinoma" which reported that there is still a lack of comprehensive analysis of the circular RNA -long non-coding RNA -miRNA-mRNA ceRNA network in hepatocellular carcinoma.

Feeling like leisure is wasteful may lead to poorer mental health outcomes, research suggests

Tue, 08/24/2021 - 08:09
Feeling like leisure is wasteful and unproductive may lead to less happiness and higher levels of stress and depression, new research suggests.

COVID booster shots might be needed in subgroup of HIV-positive individuals

Tue, 08/24/2021 - 07:57
The coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved into a global pandemic destroying lives and economies. COVID-19 is not curable, so vaccines are the only safeguard during this pandemic.

Study: Awake prone positioning can reduce the need for mechanical ventilation in COVID-19 patients

Tue, 08/24/2021 - 07:38
A six country clinical study of more than 1,100 hospitalized COVID-19 patients who required high-flow nasal cannula oxygen therapy suggests that prone positioning (rotating patients with severe breathing issues so they are face down) soon after admission can significantly reduce the need for mechanical ventilation.

Researchers unravel pathomechanisms involved in Chronic Fatigue Syndrome

Tue, 08/24/2021 - 07:07
ME (Myalgic Encephalopathy), also known as Chronic Fatigue Syndrome (CFS), can be a debilitating disease. It frequently presents after an infection, and key features are long-lasting fatigue and worsening of symptoms after exertion.