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Lead author Neta Rosenzweig, PhD, of the Ann Romney Center for Neurological Diseases, and senior author Oleg Butovsky, PhD, of the Ann Romney Center and Gene Lay Institute of Immunology and Inflammation, share key messages from their paper "Sex-Dependent APOE4 Neutrophil-Microglia Interactions Drive Cognitive Impairment in Alzheimer's Disease" published in Nature Medicine.

A new Finnish study from University of Turku shows that already a 30-minute exercise can increase the proportion of tumor-killing white blood cells in the bloodstream of breast cancer patients.

Researchers explored neutrophil involvement in visceral adipose tissue (VAT) inflammation in obesity.

Ever wondered why you performed worse than expected in that final university exam that you sat in a cavernous gymnasium or massive hall, despite countless hours, days and weeks of study? Now you have a genuine reason – high ceilings.

The association between exposure to air pollutants over extended periods and the loss of independence among older adults.

The efficacy of two versions of automated feedback following internet-based depression screening on the severity of depression.

In 2019, more than 12,000 new cases of cervical cancer were diagnosed and upwards of 4,000 patients died in the U.S. The causal link between human papillomavirus (HPV) infection and the development of cervical cancer is well documented. Cervical cancer screening guidelines are currently in the review process for updates. On May 15, 2024, the U.S. Food and Drug Administration (FDA) approved patient-collected testing (vaginal self-collection) for HPV. Several countries, including the Netherlands and Australia, have introduced HPV self-collection as a part of their national screening programs.

A promising therapy that treats blood cancers by harnessing the power of the immune system to target and destroy cancer cells could now treat solid tumors more efficiently. Thanks to a recent study published in Molecular Therapy – Methods & Clinical Development from Dan Cappabianca and Krishanu Saha at the Wisconsin Institute for Discovery, Chimeric Antigen Receptor (CAR) T-cell therapy can be improved by altering the conditions the T cells are grown in. And it was all discovered by chance.

A new groundbreaking study sheds light on a medical question scientists have long wondered: why do 40 per cent of children with the rare neurodevelopmental disorder KBG syndrome have heart defects? The research now points to a critical link between the heart and the brain.

While investigating two boys from different families with severe obesity, anxiety, autism, and behavioural problems triggered by sounds or smells, a team led by scientists at the University of Cambridge, UK, and Baylor College of Medicine, Houston, USA, discovered that the boys were missing a single gene, known as TRPC5, which sits on the X chromosome.

A multinational team led by Weill Cornell Medicine investigators developed a test that will help measure the persistence of HIV in people affected by viral strains found predominantly in Africa-;a vital tool in the search for an HIV cure that will benefit patients around the world.

Liver diseases are commonly diagnosed using serum enzyme assays, particularly for aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyl transpeptidase (GGT), and 5'-nucleotidase (5'-NT).

Transgender, nonbinary, and gender-diverse people face barriers to accessing surgery and to the health system in general, describe authors in two new research papers published in CMAJ (Canadian Medical Association Journal).

Study reveals a significant rise in ADHD diagnoses and medication use in Finland during the COVID-19 pandemic, highlighting the pandemic's impact on mental health recognition, especially among young women and older adults.

Study demonstrates that six months of high-impact unilateral exercise significantly improves femoral neck bone density in postmenopausal women without negatively affecting knee osteoarthritis progression.

Neuroendocrine tumors, including small cell lung cancer and neuroendocrine prostate cancer, are very aggressive with high chances of spreading.

A world-first study has found low-dose aspirin may treat flu-induced blood vessel inflammation, creating better blood flow to the placenta during pregnancy.

Using artificial intelligence, Garvan Institute researchers have found potential cancer drivers hidden in so-called 'junk' regions of DNA, opening up possibilities for a new approach to diagnosis and treatment.

We set out to identify genes that are commonly expressed in CD8+ T cells, killer immune cells that can drive anti-tumor immunity, across many types of human cancers.

Already at the beginning of the COVID-19 pandemic, a group of Brazilian researchers pioneered in showing why SARS-CoV-2 infection tends to be more severe in diabetic patients.